NCT07482800

Brief Summary

This study aims to compare the natural narrative language of patients with Alzheimer's disease and the fictional depictions of dementia in contemporary novels from both neurological and literary perspectives. It investigates the similarities and differences in the deterioration of semantic and episodic memory. The goal is to develop a cross-disciplinary language observation model that enhances early diagnostic understanding, fosters empathy in caregiving, and strengthens medical humanities education.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
2mo left

Started Mar 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress66%
Mar 2026Jul 2026

First Submitted

Initial submission to the registry

March 8, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

March 17, 2026

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 19, 2026

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2026

Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

5 months

First QC Date

March 8, 2026

Last Update Submit

March 18, 2026

Conditions

Keywords

DementiaLanguage DeclineNeurologyNarrative MedicineLiterary Analysis

Outcome Measures

Primary Outcomes (1)

  • Mini-Mental State Examination

    assess cognitive function, including orientation, memory, attention, language, and basic visuospatial ability

    on the day of enrollment

Study Arms (2)

Case group

Diagnosed with early-stage Alzheimer's disease or other mild cognitive impairment by a neurologist

Control group

Healthy individuals matched for age and education level

Eligibility Criteria

Age60 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patient of affiliated university hospital

You may qualify if:

  • Diagnosed with early-stage Alzheimer's disease or other mild cognitive impairment by a neurologist (case group) / healthy individuals matched for age and education level (control group)
  • Able to communicate and understand basic language

You may not qualify if:

  • Refuse to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fu Jen Catholic University Hospital, Fu Jen Catholic University

New Taipei City, 24352, Taiwan

RECRUITING

MeSH Terms

Conditions

DementiaNarrative Medicine

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersNarrationCommunicationBehavior

Study Officials

  • Ke-Yun Chao, PhD

    Fu Jen Catholic University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ke-Yun Chao, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 8, 2026

First Posted

March 19, 2026

Study Start

March 17, 2026

Primary Completion (Estimated)

July 31, 2026

Study Completion (Estimated)

July 31, 2026

Last Updated

March 20, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations