NCT07479875

Brief Summary

This study investigated the acute effects of ingesting 400 mg of caffeine administered 30 minutes before Brazilian jiu-jitsu-specific strength endurance tests. Experienced athletes completed two conditions, placebo and caffeine, in a randomized, double-blind, crossover clinical trial. Performance was assessed using the dynamic component of the kimono grip strength test (maximum number of repetitions, MNR) and the isometric component (maximum static lift, MSL), both performed with a gi grip. Rating of perceived exertion, adverse effects, and blinding effectiveness were also evaluated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 20, 2025

Completed
22 days until next milestone

Study Start

First participant enrolled

December 12, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 15, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2026

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 18, 2026

Completed
Last Updated

March 18, 2026

Status Verified

March 1, 2026

Enrollment Period

1 month

First QC Date

November 20, 2025

Last Update Submit

March 14, 2026

Conditions

Keywords

CaffeineErgogenic AidBrazilian Jiu-JitsuCombat SportsMuscular EnduranceGrip StrengthAthletesRandomized Crossover TrialDouble-Blind

Outcome Measures

Primary Outcomes (2)

  • Dynamic component of the Kimono Grip Strength Test (Maximum Number of Repetitions, MNR)

    Brazilian jiu-jitsu-specific strength endurance test performed using a kimono grip on a pull-up bar. Participants completed three maximal sets of the dynamic component of the Kimono Grip Strength Test (maximum number of repetitions, MNR), and the total number of valid repetitions was recorded.

    During each experimental session, following intervention administration (two sessions, approximately 7 days apart).

  • Isometric component of the Kimono Grip Strength Test (Maximum Static Lift, MSL)

    Maximum isometric holding time (seconds) during the isometric component of the Kimono Grip Strength Test. Participants maintained an isometric position at approximately 90 degrees of elbow flexion using a kimono grip on a pull-up bar, and the maximal hold time was recorded.

    During each experimental session, following intervention administration (two sessions, approximately 7 days apart).

Secondary Outcomes (4)

  • Interindividual Response Variability

    At study completion, after the second experimental session (two sessions approximately 7 days apart).

  • Rating of perceived exertion (Borg CR10 scale)

    During each experimental session, at the end of testing following intervention administration (two sessions, approximately 7 days apart).

  • Bang blinding index

    At the end of each experimental visit following intervention administration (two visits, approximately 7 days apart).

  • Acute Adverse Effects

    Within 24 hours after each experimental session following intervention administration (two sessions, approximately 7 days apart).

Study Arms (2)

Placebo

PLACEBO COMPARATOR

Capsule containing 400 mg of starch (placebo), ingested 30 minutes before testing.

Other: Placebo

Caffeine

EXPERIMENTAL

Capsule containing 400 mg of anhydrous caffeine, ingested 30 minutes before testing.

Dietary Supplement: Caffeine

Interventions

CaffeineDIETARY_SUPPLEMENT

Capsule containing 400 mg of anhydrous caffeine ingested 30 minutes before performance testing.

Also known as: caf
Caffeine
PlaceboOTHER

Capsule containing 400 mg of cornstarch used as placebo, ingested 30 minutes before performance testing.

Placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Adult men
  • Brazilian Jiu-Jitsu athletes
  • Minimum of 5 years of continuous practice
  • Participation in competitions within the past 12 months
  • Absence of upper-limb injuries
  • No use of caffeine or stimulant substances within 48 hours prior to testing
  • Availability to attend both experimental sessions
  • Physical fitness to perform maximal strength tests

You may not qualify if:

  • Recent musculoskeletal injuries
  • Use of stimulant substances, pre-workout supplements, or thermogenic products
  • Known hypersensitivity to caffeine
  • Clinical conditions that could limit participation (cardiovascular, respiratory, or neurological)
  • Failure to attend any experimental session
  • Noncompliance with pre-test nutritional guidelines

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidade Federal de Minas Gerais (UFMG), Laboratory of Nutrition and Exercise Training (LAN-UFMG), Belo Horizonte, MG, Brazil

Belo Horizonte, Minas Gerais, 31275000, Brazil

Location

MeSH Terms

Conditions

Motor Activity

Interventions

Caffeine

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

XanthinesAlkaloidsHeterocyclic CompoundsPurinonesPurinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-Ring

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Caffeine and placebo capsules were identical in color, size, shape, and taste. Randomization was performed by a researcher not involved in data collection. Neither the participants nor the assessors were aware of which substance was administered in each session. The allocation code was revealed only after the completion of the data analysis.
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Brazilian Jiu-Jitsu athletes completed two experimental sessions in a randomized, double-blind, crossover design. In one session, participants ingested caffeine, and in the other, they ingested a placebo, with a minimum washout period of seven days. The order of the conditions was counterbalanced across participants, and all performance assessments were conducted under both conditions.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 20, 2025

First Posted

March 18, 2026

Study Start

December 12, 2025

Primary Completion

January 15, 2026

Study Completion

January 15, 2026

Last Updated

March 18, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared due to ethical and confidentiality restrictions, as participants did not provide consent for public data sharing. Aggregated data are available in the published study reports.

Locations