Whole-body Vibration Training on the Elderly With Combined Bilateral Knee Osteoarthritis

NCT07478861 | Enrolling By Invitation

• 2 other identifiers: Faculty of Physical TherapyMariam Abdel Rahman
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance \[gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.

Conditions

Whole Body Vibration; Knee OA; Sarcopenic Obesity

Keywords

knee osteoarthritis; elderly patients; sarcopenic obesity; whole body vibration training

Outcome Measures

Primary Outcomes (1)

• Physical performance

  These are standardized tests used to assess lower limb strength, mobility, and overall functional ability in elderly patients it includes: 1. Gait speed (it is the rate a person can tolerate walking measured in meter per seconds (ask the person to walk at their usual comfortable pace for 10 meters; and record how many seconds it takes to complete this distance and evaluate the recorded time before and after the treatment); 2. 5-time chair stand test; t evaluates how quickly a participant can perform 5 successive sit-to-stand without using their arms (it evaluate the time taken to complete 5 repetitions, a. ≤ 12 seconds is considered normal physical performance, b. \> 15 seconds may indicate lower extremity weakness, mobility limitations, or increased fall risk, c. Unable to complete indicates significant functional impairment). All measurements will be carried out before the treatment and after the end of the treatment.

  8 weeks

Study Arms (2)

Elderly male patients with knee osteoarthritis

EXPERIMENTAL

Elderly male patients with knee osteoarthritis associated with sarcopenic obesity

Other: Whole-body vibration training

Elderly female patients with knee osteoarthritis

ACTIVE COMPARATOR

Elderly female patients with knee osteoarthritis associated with sacropenic obesity

Other: Whole-body vibration training

Interventions

Whole-body vibration training OTHER

Whole-body vibration therapy stimulates muscle contraction. It can increase muscle function to a level like that of classical resistance training, but with the advantage of being more convenient and safer

Elderly female patients with knee osteoarthritis; Elderly male patients with knee osteoarthritis

Eligibility Criteria

• Age: 60 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with KOA were graded based on the Kellgren-Lawrence grading criteria (K-L grading)
• only grades 3 and 4 will be included in this study
• Sarcopenia obesity based on with SMI with SMI \< 7 kg/m2
• PBF ≥ 30% into the SO group
• BMI ≥ 28%, or waist circumference ≥ 85 cm in men and ≥ 80 cm in women
• able to communicate

You may not qualify if:

• Inability to walk
• Knee joint underwent drug treatment or intra-articular injection
• Uncontrollable angina pectoris induced by exercise
• Uncontrolled hypertension, acute or chronic renal failure, or dyspnea in the resting state
• Neurological or respiratory conditions or injuries (ie, dementia, Alzheimer's disease, multiple sclerosis, chronic obstructive pulmonary disease), rheumatoid arthritis and clinical depression.

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Beni Suef University Hospital

Banī Suwayf, Egypt

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Mariam Abdel Rahman Mohamed Abd Allah Lecturer of Orthopaedic Physical Therapy

Model Details: This study will aim to evaluate the effects of whole-body vibration training (WBVT) on body composition, muscle strength (hand grip strength), and physical performance \[gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB), pain intensity, triglycerides in older people with knee OA and sarcopenic obesity in a group of Men compared to group of females.

Study Record Dates

• First Submitted: March 3, 2026
• First Posted: March 18, 2026
• Study Start: March 15, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: March 18, 2026

Record last verified: 2026-02

Locations

EG (1)