NCT07474597

Brief Summary

This study aimed to evaluate the effectiveness of popliteus muscle-targeted myofascial release techniques (MFR) when added to conventional physical therapy and rehabilitation (PTR) and exercise protocols in patients with knee pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 2, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 2, 2026

Completed
27 days until next milestone

First Submitted

Initial submission to the registry

January 29, 2026

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 16, 2026

Completed
Last Updated

March 17, 2026

Status Verified

March 1, 2026

Enrollment Period

3 months

First QC Date

January 29, 2026

Last Update Submit

March 15, 2026

Conditions

Keywords

Knee pain; Popliteus; Myofascial release; Manual therapy; Physical therapy and rehabilitation; WOMAC

Outcome Measures

Primary Outcomes (1)

  • Myofascial Release Techniques AppliMeasurement of quality of life in individuals with knee pain following myofascial release techniques applied to the popliteus muscle.

    Measurement of quality of life in individuals with knee pain following myofascial release techniques applied to the popliteus muscle. The SF-12 scale was used as the measurement. Patella circumference measurements were also taken.

    5 days 10 sessions

Study Arms (2)

Popliteus

ACTIVE COMPARATOR

Myofascial Release Techniques Applied to the Popliteus Muscle

Other: Myofascial Release

Kontrol Grubu

NO INTERVENTION

Myofascial Release uygulanmadı

Interventions

Classical Myofascial Release

Popliteus

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Being between 18-70 years of age
  • Being able to communicate in Turkish
  • Being literate
  • Having a diagnosis of non-specific knee pain, Patellafemoral pain syndrome, or Knee Osteoarthritis
  • Volunteering to participate in the study

You may not qualify if:

  • Having undergone surgery on the knee joint
  • Having a diagnosis of inflammatory rheumatism
  • Having a significant clinical infection
  • Having a fracture in the bones forming the knee joint
  • Having received cortisol treatment within the last 6 months
  • Having a disease that prevents the patient from lying prone
  • Having a history of deep vein thrombosis
  • Having severe varicose vein disease
  • Being an active cancer patient

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

İstanbul Fatih Sultan Mehmet Eğitim ve Araştırma Hastahanesi

Istanbul, Turkey (Türkiye)

Location

Related Publications (1)

  • Flandry F, Hommel G. Normal anatomy and biomechanics of the knee. Sports Med Arthrosc Rev. 2011 Jun;19(2):82-92. doi: 10.1097/JSA.0b013e318210c0aa.

MeSH Terms

Interventions

Myofascial Release Therapy

Intervention Hierarchy (Ancestors)

MassageTherapy, Soft TissueMusculoskeletal ManipulationsComplementary TherapiesTherapeuticsPhysical Therapy ModalitiesRehabilitation

Study Officials

  • Ali CIMBIZ

    Istanbul Rumeli Universitesi

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
physiotherapist

Study Record Dates

First Submitted

January 29, 2026

First Posted

March 16, 2026

Study Start

October 1, 2025

Primary Completion

January 2, 2026

Study Completion

January 2, 2026

Last Updated

March 17, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share
Shared Documents
SAP

Locations