Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis

NCT07468734 | Recruiting

• 1 other identifier: DCSR-02026-104
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.

Conditions

Shock Wave; Traditional Physical Therapy; Chronic Knee Osteoarthritis

Outcome Measures

Primary Outcomes (1)

• Change in pain intensity

  Change in pain intensity will be assessed using the Visual Analogue Scale (VAS) which is a 10-cm horizontal line used to measure pain intensity, ranging from (0) "no pain" to (10) "worst imaginable pain".

  5-week after intervention

Secondary Outcomes (4)

• Stiffness assessment

  5-week after intervention

• Assessment of physical function

  5-week after intervention

• Knee range of motion

  5-week after intervention

• Incidence of adverse events

  5-week after intervention

Study Arms (2)

ESWT Group

EXPERIMENTAL

Patients will receive extracorporeal shock wave therapy.

Other: Extracorporeal shock wave therapy

Exercise Therapy Group

ACTIVE COMPARATOR

Patients will undergo a structured exercise therapy program.

Other: Exercise therapy program

Interventions

Extracorporeal shock wave therapy OTHER

Patients will receive extracorporeal shock wave therapy.

ESWT Group

Exercise therapy program OTHER

Patients will undergo a structured exercise therapy program.

Exercise Therapy Group

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults ≥ 40 years with clinical and radiographic diagnosis of chronic knee osteoarthritis (KOA) (Kellgren-Lawrence grade II-III).
• Both sexes.
• Persistent knee pain ≥ 3 months.
• Ability to provide consent and participate in interventions.

You may not qualify if:

• Prior knee surgery within last 6 months.
• Intra-articular injections in the last 3 months.
• Systemic inflammatory arthritis or other neurological conditions affecting gait.

Sponsors & Collaborators

• German International University: lead

Study Sites (1)

German International University

Cairo, 12613, Egypt

RECRUITING

MeSH Terms

Interventions

Extracorporeal Shockwave Therapy

Intervention Hierarchy (Ancestors)

Ultrasonic Therapy; Diathermy; Hyperthermia, Induced; Therapeutics; Physical Therapy Modalities; Rehabilitation

Central Study Contacts

Magdy M Shabana, MD

CONTACT

00201006053332; magdy.shabana@giu-uni.de

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor in Orthopedic, Physical Therapy

Study Record Dates

• First Submitted: March 9, 2026
• First Posted: March 13, 2026
• Study Start: March 18, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): November 30, 2026
• Last Updated: March 19, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)