Effectiveness of Manual Therapy and Extracoropral Shock Wave Therapy in Patients With Carpal Tunnel Syndrome

NCT07074509 | Completed

• 1 other identifier: 36208/12/22
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to compare the effectiveness of manual therapy and extracorporeal shock wave therapy in patients with mild to moderate carpal tunnel syndrome.

Conditions

Manual Therapy; Extracoropral Shock Wave Therapy; Carpal Tunnel Syndrome

Outcome Measures

Primary Outcomes (1)

• Visual analogue scale

  A visual analogue scale (VAS) via 11-point numerical pain rating scale (0=no pain to 10=maximum pain) was used to assess the current level of pain and hand discomfort

  3 months post-procedure

Secondary Outcomes (1)

• Boston Questionnaire

  3 months post-procedure

Study Arms (2)

Group 1

ACTIVE COMPARATOR

Patients were treated by manual therapy in the form of nerve gliding, soft tissue release, and carpal bone mobilization, three sessions per week for 4weeks.

Other: Manual therapy

Group 2

EXPERIMENTAL

Patients were treated by extracorporeal shock wave therapy. 4 sessions, one week apart, 2000 pulses per session, intensity 1.6 mj/mm, and frequency 8Hz.

Other: Extracorporeal shock wave therapy

Interventions

Manual therapy OTHER

Patients were treated by manual therapy in the form of nerve gliding, soft tissue release, and carpal bone mobilization, three sessions per week for 4weeks.

Group 1

Extracorporeal shock wave therapy OTHER

Patients were treated by extracorporeal shock wave therapy. 4 sessions, one week apart, 2000 pulses per session, intensity 1.6 mj/mm, and frequency 8Hz.

Group 2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Both sexes.
• Patients with mild and moderate carpal tunnel syndrome (CTS).

You may not qualify if:

• Severe cases of CTS.
• History of carpal tunnel release surgery.
• Steroid injection in carpal tunnel in the past 6 months.
• Cases of thoracic outlet syndrome and cervical radiculopathy.
• Pregnant females.
• Systemic rheumatic diseases such as rheumatoid arthritis.
• Hypothyroidism.
• Patients with bleeding tendency.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Musculoskeletal Manipulations; Extracorporeal Shockwave Therapy

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Complementary Therapies; Therapeutics; Physical Therapy Modalities; Rehabilitation; Ultrasonic Therapy; Diathermy; Hyperthermia, Induced

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: July 10, 2025
• First Posted: July 20, 2025
• Study Start: February 19, 2023
• Primary Completion: November 1, 2024
• Study Completion: November 1, 2024
• Last Updated: July 20, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)