NCT07468279

Brief Summary

This study aims to clarify relations between brain oscillations and two cognitive functions: cognitive control and memory.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
54mo left

Started Mar 2026

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress8%
Mar 2026Jan 2031

First Submitted

Initial submission to the registry

March 5, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 12, 2026

Completed
1 day until next milestone

Study Start

First participant enrolled

March 13, 2026

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2031

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2031

Last Updated

March 17, 2026

Status Verified

March 1, 2026

Enrollment Period

4.8 years

First QC Date

March 5, 2026

Last Update Submit

March 16, 2026

Conditions

Cognitive ControlMemory

Outcome Measures

Primary Outcomes (1)

  • The Difference Between Incidental Memory of Faces on Error versus Correct Trials from Baseline to Post Brain Stimulation

    The hit rate for faces that appeared on error trials minus the hit rate for faces that appeared on correct trials.

    Baseline through study visit completion, a maximum of 3 hours

Study Arms (3)

Sham Stimulation

SHAM COMPARATOR

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

Device: Sham device

STARSTIM device treatment (in-phase theta)

EXPERIMENTAL

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

Device: STARSTIM Device in-phase

STARSTIM device treatment (anti-phase stimulation)

EXPERIMENTAL

Participants will be randomized to receive an active STARSTIM treatment or sham treatment.

Device: STARSTIM Device anti-phase

Interventions

Sham deviceDEVICE

Intervention which uses an inactive form of stimulation via electrodes on the scalp.

Sham Stimulation
STARSTIM Device in-phaseDEVICE

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of in-phase theta (\~3.5 to \~7.5 Hz) via electrodes on the scalp.

STARSTIM device treatment (in-phase theta)
STARSTIM Device anti-phaseDEVICE

Intervention that uses the Starstim tES device to introduce transcranial alternating current stimulation (tACS) in the form of anti-phase stimulation via electrodes on the scalp.

STARSTIM device treatment (anti-phase stimulation)

Eligibility Criteria

Age18 Years - 59 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years and older
  • Fluent in English
  • Normal or corrected-to-normal vision
  • Willing to be photographed

You may not qualify if:

  • Must not have ever had an injury to the head that's caused you to be knocked out for a period of time (e.g., from a fall, blow to the head, road traffic accident).
  • Must not have an uncorrected vision or physical disability that interferes with your ability to see stimuli presented briefly on a computer screen or click a mouse button rapidly.
  • Must not have a history of epilepsy, convulsions, or seizures (except childhood febrile seizures).
  • Must not have a history of fainting or syncope.
  • For female participants, they must not be pregnant and/or must not think they might be pregnant.
  • Must not have skin problems like eczema, dermatitis, or open wounds on the scalp.
  • Must not have had prior brain surgery.
  • Must not have any metal located in the head/neck (except for dental fillings).
  • Must not have any devices or other implants located in/near their head. This includes cochlear implants and aneurysm clips, cardiac pacemaker, or any other implanted electronic device.
  • Must not have a current (active) alcohol or substance use disorder, must have no recent history of withdrawal symptoms, and must be able to safely abstain from alcohol and non-prescribed/illicit drugs for at least 24 hours before the session.
  • Must not have any alcohol on the day of the session, must limit alcohol consumption to no more than 2 drinks (if legally permitted) in the prior 24 hours, and must not use any non-prescribed or illicit drugs in the 24 hours before the session.
  • Must not be sick with a fever, sleep-deprived, or feel dizzy, unwell, or intoxicated.
  • Must also have eaten and had fluids but not have consumed more caffeine than they typically consume.
  • Must not be taking anticonvulsant/anti-epileptic drugs or have ever taken them within their lifetime.
  • Must not be taking benzodiazepines or have taken them within the past 3 months.
  • +4 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Florida International University

Miami, Florida, 33199, United States

RECRUITING

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 5, 2026

First Posted

March 12, 2026

Study Start

March 13, 2026

Primary Completion (Estimated)

January 1, 2031

Study Completion (Estimated)

January 1, 2031

Last Updated

March 17, 2026

Record last verified: 2026-03

Locations

US(1)