GOAT (Gait Observation of Achilles Tendon)
GOAT
Characterization of Mechanical Properties of Achilles Tendon During Gait in Spastic Paresis Syndrome
2 other identifiers
observational
60
0 countries
N/A
Brief Summary
The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis (post-stroke or incomplete spinal cord injury) compared to healthy subjects, during gait.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2026
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 9, 2026
CompletedFirst Posted
Study publicly available on registry
March 12, 2026
CompletedStudy Start
First participant enrolled
June 1, 2026
ExpectedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2027
Study Completion
Last participant's last visit for all outcomes
December 1, 2027
March 12, 2026
March 1, 2026
1.5 years
March 9, 2026
March 9, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Achilles Tendon Young's Modulus
Young's modulus of the Achilles tendon (in kPa) measured at 3% tendon strain using ultrasound and dynamometry.
Day 1 (Baseline)
Secondary Outcomes (2)
Achilles Tendon and Gastrocnemius Medialis Length and Volume
Day 1 (Baseline)
Gastrocnemius Medialis Voluntary Activation
Day 1 (Baseline)
Study Arms (3)
Equinus pattern
Patients with stroke or incomplete spinal cord injury exhibiting an equinus gait pattern (excessive plantar flexion in terminal stance).
Non-equinus pattern
Patients with stroke or incomplete spinal cord injury exhibiting a non-equinus gait.
Healthy controls
Age, gender, height, and weight-matched individuals without neurological pathology.
Interventions
Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.
Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.
Evaluation includes maximal and sub-maximal isometric plantar flexion on a dynamometer with electrical stimulation, 3D quantified gait analysis synchronized with surface electromyography and ultrasound, and 3D ultrasound volume acquisition.
Eligibility Criteria
A maximum of 60 subjects will be included. Twenty will be post-stroke patients with hemiparesis, 20 will be post-incomplete spinal cord injury patients, and 20 will be healthy subjects.
You may qualify if:
- Study population:
- Post-stroke population:
- Adult male or female
- Patient who has had a stroke \> 7 days ago
- Patient hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and medical rehabilitation department of Nantes University Hospital
- Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
- Patients classified as 3 to 8 on the New Functional Ambulation Classification
- Indication to perform a quantified gait analysis as part of clinical management
- Post-spinal cord injury population:
- Adult men or women
- Patients with incomplete spinal cord injury graded ASIA AIS C or D from C2 to L5
- Patients hospitalised (in conventional hospitalisation or day hospital) in the neurological physical and occupational therapy department of Nantes University Hospital
- Patients with voluntary motor function rated between 2 and 4 on the MRC (Medical Research Council) scale at GM level
- Patients rated 13-20 on the WISCI-II scale
- Indication for a quantified gait analysis as part of clinical care
- +2 more criteria
You may not qualify if:
- Post-stroke and post-spinal cord injury population:
- Minors;
- History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g. botulinum toxin) in the plantar flexors \< 6 months;
- Patients with a progressive condition that contraindicates exertion (syrinx, cardiovascular instability);
- Peripheral pathology of the lower limb in question.
- Healthy population:
- History of calf surgery;
- History of muscle injury, fracture or sprain of the lower limb \< 3 months;
- History of neurological condition.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 9, 2026
First Posted
March 12, 2026
Study Start (Estimated)
June 1, 2026
Primary Completion (Estimated)
December 1, 2027
Study Completion (Estimated)
December 1, 2027
Last Updated
March 12, 2026
Record last verified: 2026-03