Interactive Motor Imagery in Virtual Reality
1 other identifier
interventional
79
1 country
1
Brief Summary
This project will build and test the first rehabilitation system employing virtual reality (VR)-based observation, motor imagery and execution to treat lower-limb neuropathic pain and motor dysfunction in participants with an incomplete spinal cord injury or another neurological disorder, eg. stroke: iCTuS-L (Interactive Computer-based Therapy System for legs). Patients using the system will control virtual representations of their legs to engage in entertaining gaming interactions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Oct 2009
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 24, 2014
CompletedFirst Posted
Study publicly available on registry
May 29, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2019
CompletedJanuary 7, 2020
December 1, 2019
10.2 years
April 24, 2014
January 6, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Sensorimotor Assessment
Questionnaire assessing distinct pain qualities associated with neuropathic pain, structured pain interview, questionnaire for assessing patients diagnosed as depressed and detects depression among the normal population, transcutaneous electrical stimulation of superficial nerves, information about the motor level of the lesion, the sensory levels of the lesion (light touch and pin prick), questionnaire assessing activities of daily life and independence in subjects with spinal cord lesion, walking aids and/or personal assistance, examining gait speed, transcranial magnetic stimulation
16 weeks
Study Arms (1)
Rehabilitation
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- Age between 16 and 80
- clinically incomplete spinal cord injury (time since injury: chronic \> 1 year; acute \< 3 months)
- ASI C or D
- neuropathic pain and/or motor deficits
- diagnosed neurological disorder, eg. stroke
You may not qualify if:
- any disease limiting training
- epilepsy
- major depression or psychosis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Curt, Armin, MD
Zurich, 8008, Switzerland
Related Publications (1)
Villiger M, Liviero J, Awai L, Stoop R, Pyk P, Clijsen R, Curt A, Eng K, Bolliger M. Home-Based Virtual Reality-Augmented Training Improves Lower Limb Muscle Strength, Balance, and Functional Mobility following Chronic Incomplete Spinal Cord Injury. Front Neurol. 2017 Nov 28;8:635. doi: 10.3389/fneur.2017.00635. eCollection 2017.
PMID: 29234302DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 24, 2014
First Posted
May 29, 2014
Study Start
October 1, 2009
Primary Completion
December 1, 2019
Study Completion
December 1, 2019
Last Updated
January 7, 2020
Record last verified: 2019-12