The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital

NCT07465822 | Active Not Recruiting DMC

• 1 other identifier: 154/37
• Study Type: observational
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital setting. V-NOTES hysterectomy is a minimally invasive surgical technique performed through the vaginal route that combines the advantages of laparoscopy without requiring abdominal incisions. The study will assess the progression of surgical performance of a resident performing V-NOTES hysterectomy under the supervision of an experienced attending surgeon. Key operative and postoperative outcomes will be recorded to evaluate the acquisition of surgical proficiency over time.

Conditions

Abnormal Uterine Bleeding, Unspecified; Benign Gynecological Disease; Adenomyosis of Uterus; Uterine Leiomyomas

Keywords

learning curve; hysterectomy; vaginal natural orifis; resident doctor; minimally invasive

Outcome Measures

Primary Outcomes (1)

• Operative time of V-NOTES hysterectomy

  Operative time will be defined as the time interval between the initial vaginal incision and completion of vaginal cuff closure.

  Baseline (pre-procedure), perioperative/periprocedural period

Secondary Outcomes (1)

• Intraoperative complications

  perioperative/periprocedural period

Eligibility Criteria

• Age: 18 Years - 70 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients deemed suitable for V-NOTES hysterectomy based on preoperative evaluation

You may qualify if:

• Voluntary participation in the study and provision of written informed consent
• Female patients aged between 18 and 70 years
• Patients admitted to the Department of Obstetrics and Gynecology at Çukurova -University and scheduled for elective hysterectomy
• Patients deemed suitable for V-NOTES hysterectomy based on preoperative evaluation

You may not qualify if:

• Refusal to provide informed consent
• Anatomical or technical limitations preventing placement in the lithotomy -position
• Pregnancy
• Presence of acute abdomen or indication for emergency surgery
• Presence or history of deep infiltrating endometriosis
• Suspected pelvic adhesions
• Detection of a nodule in the pouch of Douglas
• Fixed uterus on pelvic examination
• Sexually inactive patients
• History of tubo-ovarian abscess

Sponsors & Collaborators

• Cukurova University: lead

Study Sites (1)

Cukurova University

Adana, 01000, Turkey (Türkiye)

Location

Related Publications (3)

• Pickett CM,Seeratan DD,Mol BWJ,Nieboer TE,Johnson N,Bonestroo T,Aarts JW

  BACKGROUND

• Wang CJ,Go J,Huang HY,Wu KY,Huang YT,Liu YC,Weng CH

  BACKGROUND

• Aarts JW,Nieboer TE,Johnson N,Tavender E,Garry R,Mol BW,Kluivers KB

  BACKGROUND

MeSH Terms

Conditions

Metrorrhagia; Adenomyosis; Myofibroma

Condition Hierarchy (Ancestors)

Uterine Hemorrhage; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Neoplasms, Connective Tissue; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Neoplasms; Connective Tissue Diseases; Skin and Connective Tissue Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 3, 2026
• First Posted: March 12, 2026
• Study Start: April 18, 2025
• Primary Completion (Estimated): October 3, 2026
• Study Completion (Estimated): October 4, 2026
• Last Updated: March 19, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

TU (1)