Assessment of Female Sexual Function Index (FSFI) Scores at 1 Month After Endometrial Sampling Performed Under Sedo-Analgesia or Local Anesthesia

NCT07628660 | Recruiting

• 1 other identifier: CTCH-FSFI-2026-001
• Study Type: observational
• Target: 210
• Locations: 1 country
• Sites: 1

Brief Summary

Endometrial sampling is a commonly performed gynecological procedure used for the diagnosis of abnormal uterine bleeding and endometrial abnormalities. Different anesthetic techniques may be used during the procedure, including sedo-analgesia and local anesthesia. The purpose of this prospective observational study is to evaluate whether the anesthetic technique used during endometrial sampling affects female sexual function one month after the procedure. Female sexual function will be assessed using the validated Female Sexual Function Index (FSFI) questionnaire. A total of 210 women undergoing endometrial sampling at Prof. Dr. Cemil Taşcıoğlu City Hospital will be enrolled. Participants will be assigned to groups according to the anesthetic technique used during their routine clinical care. FSFI scores obtained at the one-month follow-up visit will be compared between women who underwent the procedure under sedo-analgesia and those who received local anesthesia. Secondary analyses will include comparison of FSFI scores according to symptom status and histopathological diagnosis. The findings of this study may contribute to a better understanding of the impact of anesthetic techniques on postoperative sexual health and quality of life in women undergoing gynecological procedures.

Conditions

Female Sexual Dysfunction; Endometrial Sampling; Abnormal Uterine Bleeding, Unspecified; Female Sexual Function Index (FSFI)

Keywords

Endometrial Sampling,Female Sexual Function Index,Sedo-Analgesia,Local Anesthesia,Abnormal Uterine Bleeding,Sexual Health

Outcome Measures

Primary Outcomes (1)

• Female Sexual Function Index (FSFI) Score at 1 Month

  Assessment of female sexual function one month after endometrial sampling using the validated Female Sexual Function Index (FSFI) questionnaire. Total FSFI scores will be compared between patients undergoing endometrial sampling under sedo-analgesia and those undergoing the procedure under local anesthesia.

  1 Month After Endometrial Sampling

Secondary Outcomes (1)

• FSFI Subdomain Scores at 1 Month

  1 Month After Endometrial Sampling

Other Outcomes (2)

• FSFI Scores According to Histopathological Diagnosis

  1 Month After Endometrial Sampling

• FSFI Scores According to Symptom Status

  1 Month After Endometrial Sampling

Study Arms (2)

Sedo-Analgesia Group

Patients undergoing endometrial sampling under intravenous sedo-analgesia as part of routine clinical care.

Local Anesthesia Group

Patients undergoing endometrial sampling under local anesthesia as part of routine clinical care.

Eligibility Criteria

• Age: 18 Years - 60 Years
• Gender Eligibility Details: This study is limited to individuals who identify as women, as the study evaluates female sexual function using the Female Sexual Function Index (FSFI) following endometrial sampling.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of women aged 18-60 years undergoing endometrial sampling for various gynecological indications at the Department of Obstetrics and Gynecology, Prof. Dr. Cemil Taşcıoğlu City Hospital. Participants receiving sedo-analgesia or local anesthesia as part of routine clinical care will be included. Female sexual function will be assessed one month after the procedure using the Female Sexual Function Index (FSFI), and subgroup analyses may be performed according to symptom status and histopathological diagnosis.

You may qualify if:

• Female patients aged 18 to 60 years
• Undergoing endometrial sampling at the Department of Obstetrics and Gynecology, Prof. Dr. Cemil Taşcıoğlu City Hospital
• Undergoing the procedure under sedo-analgesia or local anesthesia as part of routine clinical practice
• Attendance at the 1-month follow-up visit
• Ability to complete the Female Sexual Function Index (FSFI) questionnaire

You may not qualify if:

• Age younger than 18 years or older than 60 years
• Presence of known chronic systemic disease
• Incomplete clinical or follow-up data
• Failure to attend the 1-month follow-up visit
• Inability or unwillingness to complete the FSFI questionnaire

Sponsors & Collaborators

• Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization: lead

Study Sites (1)

Prof.Dr.Cemil Taşcıoğlu City Hospital

Istanbul, 34384, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Metrorrhagia

Condition Hierarchy (Ancestors)

Uterine Hemorrhage; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Yağmur ÖZKAN, M.D.

CONTACT

+90 5374318241; yagmurolmez92@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D., Department of Obstetrics and Gynecology

Study Record Dates

• First Submitted: June 1, 2026
• First Posted: June 5, 2026
• Study Start: April 15, 2026
• Primary Completion (Estimated): May 15, 2027
• Study Completion (Estimated): May 15, 2027
• Last Updated: June 5, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)