Evaluating Universal Adhesives in Cervical Lesions

NCT07459374 | Active Not Recruiting

• 1 other identifier: KA-23085
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this randomized controlled clinical trial is to evaluate the 12-month clinical performance of restorations placed in NCCLs using universal adhesives with different compositions according to FDI criteria.

Conditions

Cervical Lesion; Dental

Keywords

G2 Bond Universal; Scotchbond Universal Plus; Tokuyama Universal Bond II; Non-Carious Cervical Lesions

Outcome Measures

Primary Outcomes (1)

• Restoration survival rate at 12 months

  Restoration survival rate at 12 months, defined as: At least 90% of restorations remaining in situ No statistically significant difference among groups according to FDI criteria

  From baseline to 12 month

Study Arms (3)

G2 Bond Universal

EXPERIMENTAL

Enamel margins will be beveled (0.5 mm) using a flame-shaped diamond bur.Isolation will be achieved using cotton rolls and saliva ejector. Enamel surfaces will be etched with 35% phosphoric acid for 15 seconds, rinsed for 15 seconds, and dentin left slightly moist. Adhesives will be applied according to the manufacturer's instructions. A nanohybrid universal composite (OptiShade, Kerr Corporation, Orange, CA, USA) will be placed incrementally (≤2 mm layers) and light-cured. Finishing and polishing will be performed using OptiDisc discs and HiLuster polishing system (Kerr).

Device: G2 Bond Universal, GC Europe N.V., Leuven, Belgium

Scotchbond Universal Plus

EXPERIMENTAL

Enamel margins will be beveled (0.5 mm) using a flame-shaped diamond bur. Isolation will be achieved using cotton rolls and saliva ejector. Enamel surfaces will be etched with 35% phosphoric acid for 15 seconds, rinsed for 15 seconds, and dentin left slightly moist. Adhesives will be applied according to the manufacturer's instructions. A nanohybrid universal composite (OptiShade, Kerr Corporation, Orange, CA, USA) will be placed incrementally (≤2 mm layers) and light-cured. Finishing and polishing will be performed using OptiDisc discs and HiLuster polishing system (Kerr).

Device: Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA

Tokuyama Universal Bond II

EXPERIMENTAL

Enamel margins will be beveled (0.5 mm) using a flame-shaped diamond bur. Isolation will be achieved using cotton rolls and saliva ejector. Enamel surfaces will be etched with 35% phosphoric acid for 15 seconds, rinsed for 15 seconds, and dentin left slightly moist. Adhesives will be applied according to the manufacturer's instructions. A nanohybrid universal composite (OptiShade, Kerr Corporation, Orange, CA, USA) will be placed incrementally (≤2 mm layers) and light-cured. Finishing and polishing will be performed using OptiDisc discs and HiLuster polishing system (Kerr).

Device: Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan

Interventions

G2 Bond Universal, GC Europe N.V., Leuven, Belgium DEVICE

G2 Bond Universal, GC Europe N.V., Leuven, Belgium

G2 Bond Universal

Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA DEVICE

Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA

Scotchbond Universal Plus

Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan DEVICE

Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan

Tokuyama Universal Bond II

Eligibility Criteria

• Age: 18 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy individuals aged 18-55 years
• No systemic condition contraindicating restorative treatment
• Brushing teeth at least twice daily
• At least 20 teeth in occlusion
• At least three vital posterior teeth with non-carious cervical lesions and antagonist teeth
• Completed initial periodontal therapy
• Signed informed consent

You may not qualify if:

• Healthy individuals aged 18-55 years
• No systemic condition contraindicating restorative treatment
• Brushing teeth at least twice daily
• At least 20 teeth in occlusion
• At least three vital posterior teeth with non-carious cervical lesions and antagonist teeth
• Completed initial periodontal therapy
• Signed informed consent

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, 06100, Turkey (Türkiye)

Location

Study Officials

• Cansu Atalay, Assoc. Prof.

  Hacettepe University

  PRINCIPAL INVESTIGATOR

• Aybüke Uslu Tekce, Assist. Prof.

  Hacettepe University

  PRINCIPAL INVESTIGATOR

• Ayşe Rüya Yazıcı, Prof.

  Hacettepe University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator, Assoc. Prof

Study Record Dates

• First Submitted: March 4, 2026
• First Posted: March 9, 2026
• Study Start: March 19, 2024
• Primary Completion: March 19, 2025
• Study Completion (Estimated): March 19, 2028
• Last Updated: March 9, 2026

Record last verified: 2026-03

Locations

TU (1)