Modified Periosteal Tissue Graft vs Collagen Matrix for Soft Tissue Augmentation Around Implants: A Comparative Study
Modified Vascularized Interpostional Periosteal Connective Tissue Graft Versus Xenogeneic Collagen Matrix for Soft Tissue Augmentation Around Implant in Esthetic Zone (Comparative Study)
2 other identifiers
interventional
20
1 country
1
Brief Summary
This clinical trial aims to evaluate the effectiveness of the Modified Vascularized Interpositional Periosteal Connective Tissue Graft (mVIP-CTG) compared to Xenogeneic Collagen Matrix (XCM) around immediate implant in esthetic zone . This study will assess outcomes such as keratinized tissue thickness, keratinized tissue width, pink esthetic score and radiographic buccal cortex thickness over a defined follow-up period. By comparing mVIP-CTG to XCM, the study seeks to determine which method provides superior clinical and aesthetic results for best soft tissue augmentation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jan 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2024
CompletedFirst Submitted
Initial submission to the registry
January 15, 2025
CompletedFirst Posted
Study publicly available on registry
February 5, 2025
CompletedFebruary 5, 2025
January 1, 2025
8 months
January 15, 2025
January 31, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
keratinized tissue thickness
measurement of Kertinized tissue thickness around implant using endodontic file
baseline, 3 months, 6 months
keratinized tissue width
measurement of keratinized tissue width using graduated UNC-15 Probe
baseline, 3 months and 6 months
buccal cortex thickness
measurement of buccal cortex thickness using CBCT
baseline and 6 months
Secondary Outcomes (1)
pink esthetic score
baseline and 6 months
Study Arms (2)
modified vestibular interpositional periosteal connective tissue graft
EXPERIMENTAL10 patients received pedicled CTG (mVIP-CTG)
Xenogenic Collagen Membrane
EXPERIMENTAL10 patients received xenogenic collagen membrane
Interventions
10 patients received mVIP-CTG
Eligibility Criteria
You may qualify if:
- systemically healthy
- teeth indicated for extraction due to trauma or root fracture
- periodontally healthy
- Good oral health
- Selected patients of both sexes are 20-40 years old.
You may not qualify if:
- parafunctional habits
- smoking, alcoholism
- pregnancy
- lactation
- untreated periodontal diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Minia Universitylead
Study Sites (1)
Hospital of faculty of dentistry, Minia university
Minya, 61517, Egypt
Study Officials
- PRINCIPAL INVESTIGATOR
Heba Ah Abdel-maged, MSc
Minia University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Teaching assistant
Study Record Dates
First Submitted
January 15, 2025
First Posted
February 5, 2025
Study Start
January 1, 2024
Primary Completion
September 1, 2024
Study Completion
December 30, 2024
Last Updated
February 5, 2025
Record last verified: 2025-01