NCT07448259

Brief Summary

The purpose of this study is to evaluate how an Artificial Intelligence -assisted learning platform affects nurses' ability to calculate medication dosages accurately. Drug calculation is a critical skill in nursing, and errors can significantly impact patient safety. While traditional teaching methods are standard, they may not provide the personalized feedback needed for such a high-stakes task. This study compares two groups of nurses: one group using an Artificial Intelligence-driven software that provides interactive scenarios and real-time guidance, and another group receiving traditional classroom instruction. The researchers aim to determine whether the AI approach leads to: Improved theoretical knowledge of drug calculations. Enhanced clinical decision-making during medication administration. Increased nurses' confidence (self-efficacy) in performing these tasks in real clinical settings. In addition, a qualitative component conducted using focus group discussions to explore participants' acceptance, perceived usefulness, usability, and overall perceptions of the AI-assisted learning platform. This qualitative inquiry provides a deeper insight into nurses' experiences, attitudes toward AI integration in education, and their opinions regarding the effectiveness of the teaching and learning strategies used within the platform.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 22, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 18, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

March 4, 2026

Completed
Last Updated

April 1, 2026

Status Verified

February 1, 2026

Enrollment Period

3 months

First QC Date

February 18, 2026

Last Update Submit

March 27, 2026

Conditions

Keywords

Artificial IntelligenceDrug CalculationNursing KnowledgeClinical Decision-MakingSelf-EfficacyScenario-Based Learning

Outcome Measures

Primary Outcomes (1)

  • Nurses' Knowledge of Drug Calculation

    A 16-item assessment tool designed to evaluate the theoretical and practical knowledge of nurses regarding drug calculation principles (e.g., unit conversions, flow rate, and dose calculations). Each correct answer is scored "1" and each incorrect answer is scored "0". Scale Range: The total score ranges from a minimum of 0 to a maximum of 16. Interpretation: Higher scores indicate a better outcome (greater mastery of calculation principles). High (13-16): Competent level (\> 80%). Moderate (10-12): Acceptable but incomplete knowledge (60%-80%). Low (0-9): Deficient understanding (\< 60%).

    Baseline (Pre-test) and 2 weeks post-intervention (Post-test)

Secondary Outcomes (3)

  • Nurses' Drug Calculation Decision-Making Scale

    Baseline (Pre-test) and 2 weeks post-intervention (Post-test)

  • General Self-Efficacy Scale

    Baseline (Pre-test) and 2 weeks post-intervention (Post-test)

  • Nurses' Perception and Satisfaction with Artificial Intelligence-Assisted Learning (Qualitative)

    2 weeks after the completion of the AI-assisted training

Study Arms (2)

Artificial Intelligence-Assisted Learning Group

EXPERIMENTAL

Use an Artificial Intelligence-assisted platform providing scenario-based learning and real-time feedback for drug calculations.

Device: Artificial Intelligence-Assisted Drug Calculation Platform

Traditional Learning Group

EXPERIMENTAL

Participants receive the standard curriculum through traditional lectures and paper-based practice sessions.

Other: Traditional Nursing Education

Interventions

An innovative Artificial Intelligence software enhances nursing accuracy in drug calculations and clinical reasoning through scenario-based learning, providing real-time feedback and adaptive learning paths.

Artificial Intelligence-Assisted Learning Group

Standard classroom-based instruction consists of theoretical lectures and paper-based practice focusing on medication dosage calculations.

Traditional Learning Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Nurses working in multiple clinical settings, including medical-surgical, cardiovascular, or critical care units..etc.
  • Nurses are responsible for medication administration and drug dosage calculations as part of their daily clinical duties.
  • Willingness to participate in the Artificial Intelligence-assisted learning program and sign the informed consent.

You may not qualify if:

  • Nurses who had recently received specific training in drug-calculation or had any prior exposure to AI-based educational tools (within the last 6 months)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Nursing, Alexandria University

Alexandria, Alexandria Governorate, 2500, Egypt

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: This study employed a mixed-methods approach, utilizing a two-arm randomized controlled trial (RCT) design for the quantitative component and a focus group discussion for the qualitative component. This design was used to evaluate the effect of Artificial Intelligence assisted learning on nursing staff's drug calculation knowledge, clinical decision-making, and self-efficacy, while simultaneously exploring their perceptions and experiences with the AI platform.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of Medical-Surgical Nursing

Study Record Dates

First Submitted

February 18, 2026

First Posted

March 4, 2026

Study Start

September 22, 2025

Primary Completion

December 30, 2025

Study Completion

December 30, 2025

Last Updated

April 1, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared to protect the privacy and confidentiality of the participating nurses

Available IPD Datasets

Study Protocol Access

Locations