Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block

NCT07447271 | Active Not Recruiting DMC

• 1 other identifier: US-CSNRB vs FL-CTFEB
• Study Type: interventional
• Target: 330
• Locations: 1 country
• Sites: 1

Brief Summary

This study retrospectively analyzed medical records and imaging records (ultrasound images, fluoroscopy-guided images) of US-CSNRB and FL-CTFEB procedures performed at the Yangsan Pusan National University Hospital Pain Clinic outpatient department from May 1, 2019, to April 30, 2024. It compared the therapeutic effects (pain reduction), procedure-related indicators (comparison of contrast agent spread), safety (incidence of complications), and changes in analgesic usage. The primary outcome of this study is the difference in pain chage (Visual Analogue Scale, VAS) between patients undergoing US-CSNRB and FL-CTFEB. The secondary outcomes are comparison of contrast agent spread and comparison of procedure-related complication rates.

Conditions

Cervical Radiculopathy

Keywords

ultrasound; fluoroscopy; nerve block; cervical radiculopathy

Outcome Measures

Primary Outcomes (1)

• The difference in pain change

  the difference in pain change, assessed using the visual analogue scale (VAS), between patients who underwent US-CSNRB and those who underwent FL-CTFEB

  baseline, 1 month, 2 month, 3 month

Secondary Outcomes (2)

• The pattern of contrast spread

  periprocedural

• The incidence of procedure-related complications

  Periprocedural

Study Arms (2)

group U

EXPERIMENTAL

Procedure: ultrasound guided cervical selective nerve root block

group F

ACTIVE COMPARATOR

Procedure: fluoroscopy-guided cervical transforaminal epidural block

Interventions

ultrasound guided cervical selective nerve root block PROCEDURE

A patient presenting to the pain clinic with cervical neck pain and upper extremity radicular pain, whose symptoms did not improve with medication, demonstrated a positive Spurling test on physical examination, and showed cervical radiculopathy at the C3/4 to C7/T1 level on imaging studies (CT or MRI), underwent an ultrasound-guided cervical selective nerve root block

Also known as: fluoroscopic guided cervical transforaminal epidural block

group U

fluoroscopy-guided cervical transforaminal epidural block PROCEDURE

A patient presenting to the pain clinic with cervical neck pain and upper extremity radicular pain, whose symptoms did not improve with medication, demonstrated a positive Spurling test on physical examination, and showed cervical radiculopathy at the C3/4 to C7/T1 level on imaging studies (CT or MRI), underwent a fluoroscopy-guided cervical transforaminal epidural block

group F

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult male and female patients aged 18 years or older.
• Patients diagnosed with cervical radiculopathy who underwent US-guided or FL-guided procedures.
• Patients with clearly documented pain scale (VAS) assessments in medical records at the following time points: 1st visit (before the procedure), 2nd visit, 3rd visit, and at least 3 months post-procedure.
• Patients who underwent procedures for lesions in a single or adjacent two segments.

You may not qualify if:

• Patients who underwent surgical treatment within one month after the procedure due to progressive neurological deficits.
• Patients with severe systemic diseases (e.g., cancer, severe immunosuppressive disorders) that may affect pain assessment.
• Patients with severe systemic diseases (e.g., cancer, severe immunosuppressive disorders) that may affect pain assessment.

Sponsors & Collaborators

• Pusan National University Yangsan Hospital: lead

Study Sites (1)

Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, 50612, South Korea

Location

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: February 21, 2026
• First Posted: March 3, 2026
• Study Start: December 22, 2025
• Primary Completion: May 4, 2026
• Study Completion: May 4, 2026
• Last Updated: March 3, 2026

Record last verified: 2026-02

Locations

KR (1)