NCT07062718

Brief Summary

Cervical radiculopathy is a condition of cervical spinal nerve roots which occurs as a result of compression and inflammatory pathology from a space occupying lesion. Nerve flossing technique is a quick mobilization of the strained nerves which will reduce pain .This study aim to determine the effects of nerve flossing technique on pain, range of motion and disability in patients with cervical radiculopathy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
38

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 3, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

July 14, 2025

Completed
11 days until next milestone

Study Start

First participant enrolled

July 25, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 20, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2025

Completed
Last Updated

July 14, 2025

Status Verified

July 1, 2025

Enrollment Period

2 months

First QC Date

July 3, 2025

Last Update Submit

July 3, 2025

Conditions

Cervical Radiculopathy

Keywords

painrange of motiondisability

Outcome Measures

Primary Outcomes (1)

  • numeric pain rating scale

    The intensity of pain was assessed with the help of NPRS. The scale have readings that numerate from 0 to 10,beginning with least reading 0 that indicates no pain ,5 indicates moderate level of pain and 10 indicates extreme level of pain.Test-retest reliability of NPRS was high

    4 weeks

Secondary Outcomes (1)

  • goniometer

    4 weeks

Other Outcomes (1)

  • universal goniometer

    4 weeks

Study Arms (2)

Median nerve flossing technique and conventional physical therapy

ACTIVE COMPARATOR

Nerve flossing will be started from root along brachial plexus,median nerve root. Before starting the procedure ,subjects will be shown the flossing technique as it will be performed actively by the subjects. Each flossing will be performed with 10 repetitions starting from neck,arm,elbow,wrist and whole nerve flossing (12). It will be a 3 week treatment with 4 session per week (12 sessions) (12).

Other: Median nerve flossing technique and conventional physical therapy

Conventional physical therapy

ACTIVE COMPARATOR

The subjects in this group will be treated with TENS and hot pack. All the subjects will be screened according to the inclusion and exclusion criteria .Written informed consent will be taken from all the subjects before the treatment. The subjects will be allowed to withdraw the treatment any time.The subjects will be divided into 2 groups through convenience sampling.All the subjects from both group will be given trancutaneous electric nerve stimulation TENS ,hot pack, isometrics and stretching as a conventional physical therapy followed by respective group techniques The session will last for 20 -25 minutes , TENS pad will be placed in the suboccipital region and the trapezius unilaterally with hot pack simultaneously for 10 minutes

Other: Conventional physical therapy

Interventions

Median nerve flossing technique and conventional physical therapyOTHER

Median nerve flossing technique and conventional physical therapy Nerve flossing will be started from root along brachial plexus,median nerve root. Before starting the procedure ,subjects will be shown the flossing technique as it will be performed actively by the subjects. Each flossing will be performed with 10 repetitions starting from neck,arm,elbow,wrist and whole nerve flossing (12). It will be a 3 week treatment with 4 session per week (12 sessions)

Also known as: conventional physical therapy
Median nerve flossing technique and conventional physical therapy
Conventional physical therapyOTHER

The subjects in this group will be treated with TENS and hot pack. All the subjects will be screened according to the inclusion and exclusion criteria .Written informed consent will be taken from all the subjects before the treatment. The subjects will be allowed to withdraw the treatment any time.The subjects will be divided into 2 groups through convenience sampling.All the subjects from both group will be given trancutaneous electric nerve stimulation TENS ,hot pack, isometrics and stretching as a conventional physical therapy followed by respective group techniques The session will last for 20 -25 minutes , TENS pad will be placed in the suboccipital region and the trapezius unilaterally with hot pack simultaneously for 10 minutes

Conventional physical therapy

Eligibility Criteria

Age30 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Participants with 30 to 50 years of age group were taken in this study (Gore et al., 2020)
  • Patients with positive Spurling test ,cervical distraction ,cervical rotation test were included
  • Participants with positive Upper limb neural tension test for median nerve were taken into consideration
  • Patients who are having radicular symptoms and pain for more than 3 months were included

You may not qualify if:

  • Systematic disorders affecting musculoskeletal disorders e.g. Ankylosing spondylitis,rheumatic arthritis etc.
  • Patient with primary shoulder or upper limb pain origin
  • Patients with severe malignancy,COPD ,isch

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr Asif Clinic

Lahore, Punjab Province, 54920, Pakistan

Location

Related Publications (9)

  • Anandkumar S. The effect of sustained natural apophyseal glide (SNAG) combined with neurodynamics in the management of a patient with cervical radiculopathy: a case report. Physiother Theory Pract. 2015 Feb;31(2):140-5. doi: 10.3109/09593985.2014.971922. Epub 2014 Oct 20.

    PMID: 25329587BACKGROUND

  • Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine (Phila Pa 1976). 2005 Jun 1;30(11):1331-4. doi: 10.1097/01.brs.0000164099.92112.29.

    PMID: 15928561BACKGROUND

  • Cleland JA, Childs JD, McRae M, Palmer JA, Stowell T. Immediate effects of thoracic manipulation in patients with neck pain: a randomized clinical trial. Man Ther. 2005 May;10(2):127-35. doi: 10.1016/j.math.2004.08.005.

    PMID: 15922233BACKGROUND

  • Dimitrov, T., Hussain, N., & Abd-Elsayed, A. (2022). Median Nerve. Peripheral Nerve Stimulation-E-Book: A Comprehensive Guide, 82.

    BACKGROUND

  • Farooq MN, Mohseni Bandpei MA, Ali M, Khan GA. Reliability of the universal goniometer for assessing active cervical range of motion in asymptomatic healthy persons. Pak J Med Sci. 2016 Mar-Apr;32(2):457-61. doi: 10.12669/pjms.322.8747.

    PMID: 27182261BACKGROUND

  • Gore, V., Patil, H., & Chogule, A. (2020). Effect of Cervical Manual Traction, TENS and Neural Tissue Mobilization on Pain and Functional Disability in Unilateral Cervical Radiculopathy. Website: Www. Ijrrjournal. Com Original Research Article International Journal of Research and Review (Ijrrjournal. Com), 7(10), 198-200.

    BACKGROUND

  • omparison of Treatment Outcome of the Effectiveness of Isometric Exercises as Hayat, M., Siddique, R., Basharat, A., Waheed, I., Rubab, S. U., Naqvi, H., . . . Haq, F. (2023). Compared to General Exercises with Cervical Spine Mobilization in The Management of Chronic Non Specific Neck Pain. British Journal of Multidisciplinary and Advanced Studies, 4(6), 63-72.

    BACKGROUND

  • Kage, V., & Gurav, G. (2017). Effect of neural flossing technique on pain, cervical range of motion and functional ability in subjects with acute, sub-acute trapezitis: An experimental study. Int. J. Appl. Res, 3, 818-822.

    BACKGROUND

  • Karkousha, R. N., Selem, A. I., Aly, S. A., & Zahran, M. R. (2023). Mulligan mobilization technique versus neural mobilization on nerve root function in patients with cervical radiculopathy: Randomized controlled trial. Revista iberoamericana de psicologĂ­a del ejercicio y el deporte, 18(6), 670-675.

    BACKGROUND

MeSH Terms

Conditions

RadiculopathyPain

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Asif Sheikh, MBBS FCPS

    Pediatric clinic

    STUDY CHAIR

Central Study Contacts

Iqra Shahbaz, MS student

CONTACT

03059374260iqrashahbaz1286@gmail.com

Muzna Munir, PHD scholar

CONTACT

03344265125muznafmh@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 3, 2025

First Posted

July 14, 2025

Study Start

July 25, 2025

Primary Completion

September 20, 2025

Study Completion

October 20, 2025

Last Updated

July 14, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)