Risk of Pneumonia in Intubated Patients in Emergency Situations

NCT07439146 | Not Yet Recruiting

• 1 other identifier: 2025_BOUILLON MINOIS_Pneumiot
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 6

Brief Summary

Orotracheal intubation in emergency medicine is a vital procedure for ensuring adequate oxygenation and ventilation in patients with respiratory distress or in shock. However, this procedure exposes patients to complications such as pneumonia. In the matter of fact, the urgency of the procedure means that it is not possible to wait until the patient's stomach is empty. Pneumonia significantly increase patient morbidity and mortality. Therapeutic management must be early and appropriate to improve the patient's prognosis. The aim of this study is to compare the rate of pneumonia occurring in patients intubated in emergency situations with that in patients intubated in non-emergency situations in all 2024. Health data will only collected from patient's medical records.

Conditions

Pneumonia; Orotracheal Intubation

Keywords

Orotracheal intubation in emergency; Pneumonia

Outcome Measures

Primary Outcomes (1)

• Pneumonia rate in 48 hours after the start of orotracheal intubation.

  Rate of pneumonia occuring within 48 hours of the start of orotracheal intubation.

  Hour 48

Secondary Outcomes (9)

• Pneumonia rate occuring 48 hours after the start of orotracheal intubation.

  3 months

• Duration of mechanical ventilation

  Up to the end of mechanical ventilation (assessed up to 1 month)

• Duration of stay in intensive care

  Up to intensive care discharge (assessed up to 1 month)

• Duration of hospital stay

  Up to hospital discharge (assessed up to 3 months)

• Mortality rate

  Inclusion + 1 year

Study Arms (2)

Intubated patients in emergency situations

Health data will be collected only with medical's record of intubated patients in emergency situation in 2024.

Intubated patients in non emergency situations

Health data will be collected only with medical's record of intubated patients in non emergency situation in 2024.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study population is patient intubated in emergency situation and patients intubated in non-emergency situation following to the admission of intensive care in 2024.

You may qualify if:

• Adult man or woman
• Emergency and non-emergency intubated patient in 2024
• Patient hospitalized in intensive care following intubation in 2024

You may not qualify if:

• Patient under guardianship, curatorship or safeguard of justice
• Pregnant woman
• Refusal to participate

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead

Study Sites (6)

CH Aurillac

Aurillac, 15000, France

Location

CHU de Clermont-Ferrand, Clermont-Ferrand

Clermont-Ferrand, France

Location

CH du Puy en Velay

Le Puy-en-Velay, 43000, France

Location

CH de Montluçon

Montluçon, 03100, France

Location

CH de Moulins

Moulins, 03000, France

Location

CH de Vichy

Vichy, 03200, France

Location

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Jean-Baptiste BOUILLON-MINOIS

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Lise Laclautre

CONTACT

334.73.754.963; promo_interne_drci@chu-clermontferrand.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 6, 2026
• First Posted: February 27, 2026
• Study Start: February 9, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: February 27, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

FR (6)