NCT07439016

Brief Summary

A prospective study that investigates the changes in LA echocardiographic parameters after PFA for paroxysmal AF.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
4mo left

Started Nov 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress62%
Nov 2025Nov 2026

Study Start

First participant enrolled

November 1, 2025

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

November 19, 2025

Completed
3 months until next milestone

First Posted

Study publicly available on registry

February 27, 2026

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Last Updated

March 18, 2026

Status Verified

March 1, 2026

Enrollment Period

1 year

First QC Date

November 19, 2025

Last Update Submit

March 17, 2026

Conditions

Atrial Fibrillation (AF)

Keywords

atrial fibrillationcatheter ablationLA function

Outcome Measures

Primary Outcomes (1)

  • 1. Change in LAA Ev between pre- and post- PFA measurements.

    During the procedure

Study Arms (1)

Cohort 1

Measurement of the LA and LAA echocardiographic parameters pre- and post-PFA for paroxysmal AF.

Diagnostic Test: LA and LAA function measurements

Interventions

LA and LAA function measurementsDIAGNOSTIC_TEST

ICE measurements of the LA and LAA function.

Cohort 1

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients scheduled for AF ablation.

You may qualify if:

  • Age ≥18 years
  • Paroxysmal AF in sinus rhythm at procedural onset

You may not qualify if:

  • Persistent or long-standing AF
  • Prior atrial ablation
  • Significant valvular disease
  • A history of LAA closure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Kralovske Vinohrady

Prague, Czechia

RECRUITING

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Marek Hozman, MD, PhD

CONTACT

+420267161111marek.hozman@fnkv.cz

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 19, 2025

First Posted

February 27, 2026

Study Start

November 1, 2025

Primary Completion (Estimated)

November 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

March 18, 2026

Record last verified: 2026-03

Locations

CZ(1)