Trauma Exposure and Suicidal Behaviors in Adolescents Aged 11-17 Hospitalized in Child and Adolescent Psychiatry

NCT07430566 | Not Yet Recruiting

• 2 other identifiers: RECHMPL25_03122025-A02017-42
• Study Type: interventional
• Target: 120
• Locations: 0 countries
• Sites: N/A

Brief Summary

It is a comparative monocentric study with longitudinal follow-up at 6 months in adolescents aged between 11 years and 17 years inclusive admitted to complete hospitalization either for suicidal behaviors or for other psychiatric causes. The objective is to explore the experiences of hospitalized adolescents regarding hospitalization, as well as their perceptions of the factors involved in their remission and their experience of the traumatic event(s) if they have been exposed.

Conditions

Suicidal Ideation and Behavior; Psychiatric Hospitalization

Keywords

suicide; adolescent; post-traumatic stress disorder; neurodevelopmental disorders; résilience; biomarqueurs; comportements suicidaires

Outcome Measures

Primary Outcomes (1)

• CPC Questionnaire child version

  This questionnaire evaluates the symptoms of PTSD and their frequency in children aged 7 to 18 years, following a traumatic event. Completion time is 15-20 minutes and the total score can range from 0 (no symptoms) to 84 (maximum symptoms) for symptom intensity and from 0 (no functional impact) to 24 (maximum functional impact) for functional impairment. The scale will be administered by a clinician (psychologist or psychiatrist for children and adolescents).

  Baseline

Secondary Outcomes (17)

• CPC questionnaire parents version

  Baseline

• Questionnaire Life Event Checklist (LEC-5)

  Baseline

• Schedule for Affective Disorders and Schizophrenia for school-age children (KSADS) full-life version

  Baseline

• Post-traumatic Stress Disorder Checklist for DSM-5 (PCL-5)

  Baseline

• Affective Reactivity Index (ARI)

  Baseline

Study Arms (2)

suicide group

ACTIVE COMPARATOR

adolescents aged between 11 years old and 17 years inclusive admitted to hospital for suicidal behaviors

Biological: Blood samples; Genetic: genetic analysis; Other: Questionnaires and scales

non-suicidal group

ACTIVE COMPARATOR

aged between 11 years old and 17 years inclusive admitted to hospital for other psychiatric causes without a history of suicidal behavior

Biological: Blood samples; Genetic: genetic analysis; Other: Questionnaires and scales

Interventions

Blood samples BIOLOGICAL

A blood test will be carried out during the inclusion visit, on site, with collection of the time of completion, the last food samples and tobacco consumption. A 2.5 mL Paxgene® tube for whole blood RNA and a 5 mL dry tube for serum will be collected.

non-suicidal group; suicide group

genetic analysis GENETIC

If consent for genetic analyses is obtained, a 4.5 mL EDTA tube to collect native DNA will be taken during the blood test

non-suicidal group; suicide group

Questionnaires and scales OTHER

* Child Posttraumatic Checklist (CPC) * Life Event Checklist (LEC-5) * Posttraumatic CheckList-5 * K-SADS * Affective Reactivity Index (ARI) * Child Youth Resilience Measure * Adverse Childhood Experiences International Questionnaire (ACE-IQ) * Metacognitions Questionnaire (MCQ-A) * Cognitive Emotion Regulation Questionnaire (CERQ) * Adolescent Dissociative Experience Scale (A-DES) * Behavioral Rating Inventory of Executive Function Self-Report (BRIEF-2)

non-suicidal group; suicide group

Eligibility Criteria

• Age: 11 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Age between 11 and 17 years inclusive
• Admitted for full-time psychiatric hospitalization
• Obtaining consent from at least one of the adolescent's legal representatives and the adolescent's personal assent
• \- Reason for admission: suicidal behavior (suicide attempt)
• \- Reason for admission: other psychiatric causes (including suicidal thoughts without suicide attempt and non-suicidal self-injurious behavior)

You may not qualify if:

• \- Neither parent available to participate in the intervention
• \- History of suicidal behavior prior to the current hospitalization

Sponsors & Collaborators

• University Hospital, Montpellier: lead

MeSH Terms

Conditions

Suicidal Ideation; Behavior; Suicide; Stress Disorders, Post-Traumatic; Neurodevelopmental Disorders

Interventions

Blood Specimen Collection; Genetic Testing; Surveys and Questionnaires; Weights and Measures

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques; Genetic Techniques; Genetic Services; Health Services; Health Care Facilities Workforce and Services; Diagnostic Services; Preventive Health Services; Data Collection; Epidemiologic Methods; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

Hala KERBAGE

CONTACT

0601819449; hala.kerbage@chu-montpellier.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Comparative study, monocentric, longitudinal, with follow-up at 6 months

Study Record Dates

• First Submitted: February 18, 2026
• First Posted: February 24, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): September 1, 2027
• Last Updated: February 24, 2026

Record last verified: 2026-02