Blood Glucose Screening in Patients With Advanced Periodontits: the Role of Specialist Periodontal Care in Identifying Hyperglycaemia and Supporting Patient Centered Treatment

NCT07426224 | Enrolling By Invitation

• 1 other identifier: FTV 2510-0527
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Periodontitis is a chronic inflammatory disease and individuals with advanced periodontitis have an increased risk of hyperglycaemia. Bacterial plaque, smoking and elevated blood glucose levels are considered key modifiable risk factors for periodontal disease progression. Conventional periodontal care aims to remove and control bacterial deposits and to smoking cessation. Despite the bidirectional relationship, where periodontitis may also contribute to impaired glycaemic control, glycaemic status is rarely niether assessed nor adressed in dental care. The aim of this project is to implement and evaluate routine blood glucose testing as part of the periodontal examination in specialist dental care. Patients diagnosed with advanced periodontitis (Stage III or IV according to the current classification) will be offered capillary blood glucose testing during their periodontal assessment. The objectives of this study are to determine the prevalence of hyperglycaemia among patients with advanced periodontitis and to evaluate clinician-reported and patient-reported experiences of routine blood glucose testing as part of the periodontal assesment in specialist periodontal care.

Conditions

Periodontitis Stage III; Periodontitis Stage IV; Diabetes (DM); Prediabetes; Hyperglycaemia

Keywords

Periodontitis stage IV; Periodontitis stage III; Diabetes; Prediabetes; Hyperglycaemia; Screening

Outcome Measures

Primary Outcomes (1)

• HbA1c mmol/mol

  The primary outcome measure is HbA1c expressed in mmol/mol, analyzed as a continuous variable and categorized according to established clinical thresholds. Descriptive statistical analyses are used to summarize HbA1c distributions and prevalence estimates in relation to periodontal characteristics.

  The bloodsampling is done chair-side and is analysed immediatley with a Point-of-Care device meaning the procedure is limited to maximum 5 minutes.

Secondary Outcomes (1)

• Hyperglycaemia

  As previously described, for the patients the capillary bloodsample is collected and analyzed in maximum 5 minutes

Interventions

Selective screening of blood glucose/HbA1c OTHER

Selective screening for hyperglycaemia in dental setting is a new routine that has not been introduced in Folktandvården Stockholm.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients referred for evaluation and treatment of periodontitis at the specialist clinic Folktandvarden Eastmaninstitutet who, following a full periodontal examination and radiographic assessment, are classified as having Stage III or Stage IV periodontitis according to current international criteria.

You may qualify if:

• adult patients \>18 years
• classified as having Stage III or Stage IV periodontitis (according to current international criteria)

You may not qualify if:

• Patients who are unable to provide informed consent because of significant cognitive impairment or unable to understand written and spoken Swedish
• Patients with periodontitis as a manifestation of systemic disease or syndrome

Sponsors & Collaborators

• Folktandvården Stockholms län AB: lead

Study Sites (1)

Folktandvården Eastmaninstitutet Parodontologi

Stockholm, 10231, Sweden

Location

MeSH Terms

Conditions

Periodontitis; Diabetes Mellitus; Prediabetic State; Hyperglycemia

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 16, 2026
• First Posted: February 23, 2026
• Study Start: March 13, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: May 11, 2026

Record last verified: 2026-05

Locations

SE (1)