Rebound Therapy on Ventilatory Functions in Down Syndrome

NCT07425353 | Not Yet Recruiting DMC

• 1 other identifier: P.T.REC/012/006209
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to examine the effects of rebound therapy on ventilatory functions in children with Down Syndrome.

Conditions

Down Syndrome

Keywords

Mini-Trampoline; Spirometry; Down Syndrome

Outcome Measures

Primary Outcomes (2)

• Forced Vital Capacity (FVC)

  Spirometry will be used to measure forced vital capacity (FVC). It is the maximum volume of gas that can be expired when the child exhales as forcefully and as rapidly as possible after a maximal inspiration to assess the overall ability to move air in and out of the lungs. It is expressed in liter/minute.

  Up to 12 weeks

• Forced Expiratory Volume in the First Second (FEV1)

  Spirometry will be used to measure forced expiratory volume in the first second (FEV1). It is the volume of gas expired over a given time interval (the first second) from the beginning of the FVC maneuver that reflects airflow in the large airways. It is expressed in liter/minute.

  Up to 12 weeks

Secondary Outcomes (2)

• Chest Expansion

  Up to 12 weeks

• Functional Mobility

  Up to 12 weeks

Study Arms (2)

Chest Physical Therapy Protocol

ACTIVE COMPARATOR

Children with Down Syndrome will receive a chest physical therapy exercises

Other: Chest Physical Therapy Protocol

Rebound Therapy Protocol

EXPERIMENTAL

Children with Down Syndrome will receive a chest physical therapy exercises in addition to rebound therapy using mini trampoline.

Other: Chest Physical Therapy Protocol; Other: Rebound Therapy Protocol

Interventions

Chest Physical Therapy Protocol OTHER

The chest physical therapy protocol include respiratory exercises and incentive spirometer training.

Chest Physical Therapy Protocol; Rebound Therapy Protocol

Rebound Therapy Protocol OTHER

The chest physical therapy protocol include respiratory exercises and incentive spirometer training + rebound therapy protocol using mini-trampoline training

Rebound Therapy Protocol

Eligibility Criteria

• Age: 9 Years - 13 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children ages will be ranged from 9 to 13 years old.
• Mild and moderate mental retardation with IQ level between 50-70 based on Stanford-Binet intelligence scale.
• Functional hearing and vision.
• Independent standing and walking.

You may not qualify if:

• Symptomatic pain.
• Musculoskeletal problems or/ atlanto-axial instability.
• Rheumatic and congenital heart disease
• History of previous surgical operation
• Regular participation in any sport activities.

Sponsors & Collaborators

• Beni-Suef University: lead

MeSH Terms

Conditions

Down Syndrome

Condition Hierarchy (Ancestors)

Intellectual Disability; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Abnormalities, Multiple; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Chromosome Disorders; Genetic Diseases, Inborn

Central Study Contacts

Eman Wagdy, PH.D

CONTACT

01008079576; Eman.wagdy@pt.bsu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 15, 2026
• First Posted: February 20, 2026
• Study Start: February 22, 2026
• Primary Completion: May 22, 2026
• Study Completion: May 22, 2026
• Last Updated: February 20, 2026

Record last verified: 2026-02