Effects of Powerball in Children With Down Syndrome

NCT07244133 | Recruiting DMC

• 1 other identifier: REC/RCR&AHS/Aymun Javed
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This randomised clinical trial investigates the effects of powerball using static and dynamic surface on upper limb Endurance and coordination in children with Down Syndrome. The study involves 28 children with Down Syndrome aged 6-10 years, will be randomly assigned one of the two groups for 3 week intervention period. Power ball training 3 sessions per week with the duration of 30 mins each session. Group A will receive different upper extremity activities with power ball on static surface while Group B will receive same activities with power ball on dynamic surface using a BOSU ball. The whole session followed by warm up and cool down sessions for 5 minutes each. Endurance will be assessed through ABIL-HAND kids tool. To access the coordination BOT-2 subsets test will be used. Data will be assessed using SPSS 27.0.

Conditions

Down Syndrome

Keywords

Down Syndrome (DS); Powerball,; Upper extremity, Children

Outcome Measures

Primary Outcomes (1)

• ABIL-HAND

  ABIL-HAND Kids Tool is used for the assessment of upper extremity endurance. It's a parent-reported measure of a child's manual ability (unilateral and bilateral hand use) in everyday tasks. Parents rate each of 21 activities as Impossible / Difficult / Easy. The item difficulty increases with bimanual involvement. The responses are expressed in form of logits. 0.90 is the reliability with a validity of 0.77

  Baseline- 1st week and 3rd week

Secondary Outcomes (1)

• BOT-2

  Baseline- 1st week and 3rd week

Study Arms (2)

The intervention will be power ball exercises on static surface

EXPERIMENTAL

Participants will undergo 3 weeks power ball endurance training session, consisting of structured, repetitive and goal directed activities. Power ball training 3 sessions per week with the duration of 30 mins each session. Group A will receive different upper extremity activities with power ball on static surface.The whole session followed by warm up and cool down sessions for 5 minutes each.Endurance will be assessed through ABIL-HAND kids tool. To access the coordination BOT-2 subsets test will be used. Data will be assessed using SPSS 27.0.

Other: Power ball with static surface

The intervention will be powerball exercises on dynamic surface

EXPERIMENTAL

Participants will undergo 3 weeks power ball endurance training session, consisting of structured, repetitive and goal directed activities. Power ball training 3 sessions per week with the duration of 30 mins each session. Group B will receive different upper extremity activities with power ball on dynamic surface.The whole session followed by warm up and cool down sessions for 5 minutes each. Endurance will be assessed through ABIL-HAND kids tool. To access the coordination BOT-2 subsets test will be used. Data will be assessed using SPSS 27.0.

Other: Powerball with dynamic surface

Interventions

Power ball with static surface OTHER

Participants will undergo 3 weeks power ball endurance training session, consisting of structured, repetitive and goal directed activities. Power ball training 3 sessions per week with the duration of 30 mins each session. Group A will receive different upper extremity activities with power ball on static surface. The whole session followed by warm up and cool down sessions for 5 minutes each.

The intervention will be power ball exercises on static surface

Powerball with dynamic surface OTHER

Participants will undergo 3 weeks power ball endurance training session, consisting of structured, repetitive and goal directed activities. Power ball training 3 sessions per week with the duration of 30 mins each session.Group B will receive same activities with power ball on dynamic surface using a BOSU ball. The whole session followed by warm up and cool down sessions for 5 minutes each.

The intervention will be powerball exercises on dynamic surface

Eligibility Criteria

• Age: 6 Years - 10 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children with Down Syndrome
• Aged between 6-10 years
• Both Genders
• Ability to follow commands and instructions

You may not qualify if:

• Children with any orthopedic and neurological conditions associated with the syndrome • Children with any other Genetic disorder.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Imran Amjad

Lahore, Punjab Province, 5400, Pakistan

RECRUITING

Related Publications (1)

• Blazquez-Fernandez A, Lopez-Hazas-Jimenez G, Fernandez-Vazquez D, Navarro-Lopez V, Fernandez-Gonzalez P, Marcos-Anton S, Molina-Rueda F, Cano-de-la-Cuerda R. Effects of the powerball(R) system on muscle strength, coordination, fatigue, functionality and quality of life in people with multiple sclerosis. A randomized clinical trial. J Neuroeng Rehabil. 2024 Mar 2;21(1):33. doi: 10.1186/s12984-024-01325-w.

  PMID: 38431591 BACKGROUND

MeSH Terms

Conditions

Down Syndrome

Condition Hierarchy (Ancestors)

Intellectual Disability; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Abnormalities, Multiple; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Chromosome Disorders; Genetic Diseases, Inborn

Study Officials

• AYMUN JAVED, MSPT

  Ripha International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

IMRAN Amjad, PHD

CONTACT

9233224390125; imran.amjad@riphah.edu.pk

MUHAMMAD ASIF JAVED, MSPT

CONTACT

923224209422; a.javed@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants will get separate treatment protocols and possible efforts will be put to mask the both group about the treatment.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized Clinical Trial (RCT) will be conducted on 28 children aged 6-10 years, diagnosed with Down Syndrome with reduced upper extremity endurance and coordination.. After screening participants will undergo 3 weeks power ball endurance training session, consisting of structured, repetitive and goal directed activities. Power ball training 3 sessions per week with the duration of 30 mins each session. Group A will receive different upper extremity activities with power ball on static surface while Group B will receive same activities with power ball on dynamic surface using a BOSU ball. The whole session followed by warm up and cool down sessions for 5 minutes each. Endurance will be assessed through ABIL-HAND kids tool. To access the coordination BOT-2 subsets test will be used. Data will be assessed using SPSS 27.0.

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 24, 2025
• Study Start: October 22, 2025
• Primary Completion: June 2, 2026
• Study Completion (Estimated): June 16, 2026
• Last Updated: November 24, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)