Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

40 trials with published results (13%)

Research Maturity

189 completed trials (59% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.0%

16 terminated out of 319 trials

Success Rate

92.2%

+5.6% vs benchmark

Late-Stage Pipeline

5%

16 trials in Phase 3/4

Results Transparency

21%

40 of 189 completed with results

Key Signals

40 with results92% success16 terminated

Data Visualizations

Phase Distribution

226Total
Not Applicable (170)
P 1 (11)
P 2 (29)
P 3 (12)
P 4 (4)

Trial Status

Completed189
Recruiting50
Unknown31
Terminated16
Active Not Recruiting12
Not Yet Recruiting12

Trial Success Rate

92.2%

Benchmark: 86.6%

Based on 189 completed trials

Clinical Trials (319)

Showing 20 of 20 trials
NCT03914625Phase 3Active Not Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

NCT06043440Phase 2RecruitingPrimary

Down Syndrome Obstructive Sleep Apnea

NCT07578922Not ApplicableCompletedPrimary

Effects of Bean Bag Tossing Game on Balance and Gait in Children With Down Syndrome.

NCT07238465Phase 3RecruitingPrimary

Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome

NCT07484464Not ApplicableCompletedPrimary

Effects of the Otago Exercise Program on Balance, Endurance, and Motor Coordination in Children With Down Syndrome

NCT03210675Not ApplicableCompletedPrimary

Early Detection and Treatment of Obstructive Sleep Apnoea in Infants With Down Syndrome

NCT07531940Phase 1Not Yet RecruitingPrimary

Escalating Doses of Memantine in Down Syndrome (MEDS-123)

NCT07816120Not ApplicableCompletedPrimary

Comparative Study of Two Applications on Muscle Strength, Balance and Motor Function in Children With Down Syndrome.

NCT05508971Not ApplicableRecruiting

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

NCT07807540Not Yet RecruitingPrimary

Hematological Profile in Children With Numerical Chromosomal Disorders

NCT01429389RecruitingPrimary

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

NCT05755464WithdrawnPrimary

Evaluation of Patients With Down Syndrome Compliance to Dental Therapy

NCT07280468Phase 4Recruiting

Endotype DIrected Treatment for OSA in Down Syndrome

NCT05662228Phase 2CompletedPrimary

Therapies for Down Syndrome Regression Disorder

NCT07296861Not ApplicableActive Not RecruitingPrimary

HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome

NCT07598643Phase 2RecruitingPrimary

Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1

NCT04546399Phase 2RecruitingPrimary

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

NCT07792382Not ApplicableNot Yet RecruitingPrimary

Executive Function Play Opportunities for Children With Down Syndrome

NCT07786545Not ApplicableNot Yet Recruiting

Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment

NCT05702645Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

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