Down Syndrome
306
49
63
173
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Published Results
39 trials with published results (13%)
Research Maturity
173 completed trials (57% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
5.2%
16 terminated out of 306 trials
91.5%
+5.0% vs benchmark
6%
17 trials in Phase 3/4
23%
39 of 173 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 173 completed trials
Clinical Trials (306)
Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy
Patterns of Neurodevelopmental Disorders
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
Gamma Frequency Stimulation in Individuals With Down Syndrome
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
Effects of the Otago Exercise Program on Balance, Endurance, and Motor Coordination in Children With Down Syndrome
Sleep Intervention and Quality of Life in Down Syndrome
Qualitative Exploratory Study Among Reunionese Women and Their Partners Who Have a Child With Trisomy 21
Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
Brain Outcomes With Lifestyle Change in Down Syndrome
Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Therapies for Down Syndrome Regression Disorder
Effects of Jump Rope on Navicular Drop in Down Syndrome
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Physical Activity and Community EmPOWERment Project