Down Syndrome
310
54
66
178
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Published Results
40 trials with published results (13%)
Research Maturity
178 completed trials (57% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
5.2%
16 terminated out of 310 trials
91.8%
+5.2% vs benchmark
5%
17 trials in Phase 3/4
22%
40 of 178 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 178 completed trials
Clinical Trials (310)
How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
tDCS for Catatonic Depression in Down Syndrome: A Pilot Study
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
Home and Community Use of a Suspension Walker in Pre-Walking Infants With Down Syndrome
Collaboration for Down Syndrome Progress (CDP)
Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1
Drumming Lessons' Influence on Children With Down Syndrome
Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition
Trial-Ready Cohort-Down Syndrome (TRC-DS)
ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
Effects of Aerobic-Based Virtual Reality Exercise Training and Traditional Aerobic Exercise Training on Physical Fitness, Functional Capacity and Cognitive Function in Individuals With Down Syndrome
Effects of Bean Bag Tossing Game on Balance and Gait in Children With Down Syndrome.
Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia