Effects of E-Cigarette Use Among Young Egyptian Adults

NCT07422415 | Completed

• 1 other identifier: R.25.09.3347
• Study Type: observational
• Target: 104
• Locations: 1 country
• Sites: 1

Brief Summary

Electronic cigarettes (E-cigarettes) have gained significant popularity as an alternative to traditional combustible tobacco cigarette smoking. E-cigarettes are marketed as a safer alternative to conventional smoking forms. Many chronic smokers suppose that e-cigarettes are risk-free and can be used effectively as a smoking cessation tool. The market size of e-cigarette is increasing because of its rising popularity among the youth even though it is not an approved Food and Drug Administration (FDA) product yet

Conditions

E Cigarette Use

Keywords

E-cigarettes; Vaping

Outcome Measures

Primary Outcomes (3)

• Spirometer parameters assessment

  Spirometry was performed to measure forced expiratory volume at 1st second (FEV₁)

  3 months

• Spirometer assessment

  Spirometry was performed to measure FEV₁/FVC ratio

  3 months

• Spirometer

  Spirometry was performed to measure forced vital capacity (FVC)

  3 months

Study Arms (2)

Non-smoker controls

Patients were included with Age ≥ 18 years, Non smokers

Diagnostic Test: Pulmonary Function test

Exclusive e-cigarette users

Patients were included if Age ≥ 18 years, Exclusive e-cigarette users (Participants were considered exclusive e-cigarette users if they had used e-cigarettes regularly for ≥ 6 months).

Diagnostic Test: Pulmonary Function test

Interventions

Pulmonary Function test DIAGNOSTIC_TEST

Spirometry was performed measure forced expiratiory volume at 1st second (FEV₁), forced vital capacity (FVC), and FEV₁/FVC ratio.

Exclusive e-cigarette users; Non-smoker controls

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 104 participants were enrolled and allocated into two equal groups: Group I: Exclusive e-cigarette users (n = 52) and Group II: Non-smoker controls (n = 52).

You may qualify if:

• Age \> 18 years
• E-cigarette users (≥6 months of regular use)
• No prior history of chronic pulmonary disease

You may not qualify if:

• Dual users (both e-cigarettes and traditional tobacco)
• History of chronic respiratory illnesses (e.g., asthma, COPD)
• immunocompromised
• Systemic chronic diseases

Sponsors & Collaborators

• Mansoura University Hospital: lead

Study Sites (1)

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

Location

MeSH Terms

Conditions

Vaping

Interventions

Respiratory Function Tests

Condition Hierarchy (Ancestors)

Smoking; Behavior

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Respiratory System; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Mohamed AbdElmoniem

  Lecturer of chest medicine faculty of medicine Mansoura university

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer faculty of medicine

Study Record Dates

• First Submitted: February 12, 2026
• First Posted: February 20, 2026
• Study Start: September 1, 2025
• Primary Completion: December 31, 2025
• Study Completion: February 1, 2026
• Last Updated: February 20, 2026

Record last verified: 2026-02

Locations

EG (1)