NCT07420933

Brief Summary

The goal of this clinical trial is to compare the impact of pea protein or whey protein supplementation during a progressive resistance exercise (PRE) regimen on body composition and strength in young adults who are not undergoing regular strength training. The main questions it aims to answer are:

  • Consume Pea or Whey protein supplement twice daily for 8 weeks
  • Participate in a PRE training program twice weekly for approximately 1.5 hours per day

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 3, 2024

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 6, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 6, 2025

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

December 19, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 19, 2026

Completed
Last Updated

February 19, 2026

Status Verified

December 1, 2025

Enrollment Period

1.8 years

First QC Date

December 19, 2025

Last Update Submit

February 16, 2026

Conditions

Keywords

pea protein isolatewhey protein isolateprogressive resistance exercisebody compositionstrengthessential amino acid

Outcome Measures

Primary Outcomes (2)

  • Difference in body composition

    Differences in lean mass (kg, kg/m\^2, and % total mass) and fat mass (kg, and % total mass) assessed using Dual Energy X-ray Absorptiometry (DXA; Horizon W, Hologic, Marlborough, MA)

    Baseline and 8 weeks

  • Difference in muscle strength

    Differences in muscle strength assessed by maximal isometric force produced by quadriceps (Nm) using a Biodex System 3 dynamometer, hand grip (kg) using a handgrip dynamometer, 1-Rep Max for chest press (kg), and 1-Rep Max for leg press (kg)

    Baseline and 8 weeks

Secondary Outcomes (1)

  • Nutritional Metabolic Biomarkers

    Baseline and 8 weeks

Other Outcomes (3)

  • Resting Metabolic Rate

    Baseline and 8 weeks

  • Blood Pressure

    Baseline and 8 weeks

  • Weight status

    Baseline and 8 weeks

Study Arms (2)

Pea Protein

EXPERIMENTAL

Participants in this arm will consume pea protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

Dietary Supplement: Protein IsolateBehavioral: Progressive Resistance Exercise Training (PRE)

Whey Protein

ACTIVE COMPARATOR

Participants in this arm will consume whey protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

Dietary Supplement: Protein IsolateBehavioral: Progressive Resistance Exercise Training (PRE)

Interventions

Protein IsolateDIETARY_SUPPLEMENT

Participants in this arm will consume protein isolate (24g/sachet) twice daily for 8 weeks.

Pea ProteinWhey Protein

Based on the resistance training guidelines from the American College of Sports Medicine, each subject will attend two supervised resistance training sessions weekly for a duration of 8 weeks. A minimum two day rest between PRE sessions will be required. Twelve exercises that targets each major muscle group will be conducted at each exercise session in the order listed below: 1. Seated chest press 2. Lat pulldown 3. Military Press 4. Seated row 5. Bicep Curl 6. Triceps Extension 7. Leg Press 8. Leg extension 9. Leg Curl 10. Heel Raise 11. Abdominal curls 12. Back extension At the first exercise session, each subject's 1-RM will be estimated for the exercises listed above

Pea ProteinWhey Protein

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy Adults 18-30y
  • BMI between 18.5 - 28 kg/m\*\*2
  • The subjects will be excluded if:
  • they have a history or current diagnosis of cardiovascular disease, cancer, diabetes, gastrointestinal disorders, or metabolic disorders.
  • they use tobacco products
  • consume alcohol as defined as \>2 drinks per day,
  • follow a special diet
  • reported recent significant body weight changes (\>5% prior 3 months)
  • report an intolerance or allergy to ingredients in the supplements.
  • report regular consumption of other muscle or metabolic stimulating products or drugs such as creatine, other amino acids or protein supplements, growth hormone or derivatives, or ergogenic aids including steroids.
  • if they answer "no" to any question on the Physical Activity Readiness Questionnaire which would indicate that the subject cannot safely participate in an exercise program.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Texas Woman's University Institute of Health Sciences Houston Center

Houston, Texas, 77008, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2025

First Posted

February 19, 2026

Study Start

February 3, 2024

Primary Completion

December 6, 2025

Study Completion

December 6, 2025

Last Updated

February 19, 2026

Record last verified: 2025-12

Locations