NCT07416643

Brief Summary

Abnormal postprandial blood glucose (PPG) is considered as a strong predictor for developing metabolic diseases worldwide. Nowadays, little understanding is available on how a carbohydrate-rich food matrix and the starch structures within interact with the gastrointestinal tract to help in controlling PPG. In this investigation, the use Acacia gum enriched flour will be used to explore the effect of adding the gum as food supplement on PPG in healthy humans.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2023

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2023

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

January 30, 2026

Completed
19 days until next milestone

First Posted

Study publicly available on registry

February 18, 2026

Completed
Last Updated

February 18, 2026

Status Verified

February 1, 2026

Enrollment Period

3 months

First QC Date

January 30, 2026

Last Update Submit

February 10, 2026

Conditions

Health Adult Subjects

Outcome Measures

Primary Outcomes (1)

  • postprandial blood glucose

    0 minutes and postprandial timepoints: 15 minutes, 30 minutes, 60 minutes,120 minutes,180 minutes

Study Arms (2)

Acacia gum incorporated biscuits

EXPERIMENTAL

Acacia gum incorporated biscuits

Dietary Supplement: incorporating acacia gum flour into commonly consume foods

control biscuits

NO INTERVENTION

control biscuits

Interventions

incorporating acacia gum flour into commonly consume foodsDIETARY_SUPPLEMENT

incorporating acacia gum flour into commonly consume foods

Acacia gum incorporated biscuits

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male and female self-reported healthy volunteers (aged 18 to 40 years)
  • Normal to overweight individuals (body mass index (BMI) 18.5-30 kg/m2) o BMI is equal to body weight (kg) divided by height squared (m2)

You may not qualify if:

  • History of substance abuse
  • Excessive alcohol intake
  • Pregnancy
  • Diabetes
  • Cardiovascular disease
  • Cancer
  • Any gastrointestinal disease e.g. irritable bowel syndrome or inflammatory bowel disease
  • Kidney disease
  • Liver disease
  • Pancreatitis
  • Use of medications likely to interfere with energy metabolism, appetite regulation and hormonal balance, including: anti-inflammatory drugs or steroids, antibiotics, androgens, phenytoin, erythromycin or thyroid hormones.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

King Fahd Medical Research center

Jeddah, Saudi Arabia

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

January 30, 2026

First Posted

February 18, 2026

Study Start

June 1, 2023

Primary Completion

August 30, 2023

Study Completion

September 30, 2023

Last Updated

February 18, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

SA(1)