NCT07243613

Brief Summary

This study examined how the body and mood respond to intense physical effort in elite male and female rowers. Athletes completed a maximal rowing test after one week of hard training. Researchers collected blood samples before and after exercise to measure stress hormones and brain-related chemicals. They also used a short questionnaire to assess how the athletes felt emotionally before the test. The goal of the study is to better understand how physical and mental fatigue develop in well-trained athletes, and whether men and women respond differently.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 15, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2025

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2025

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

November 14, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

November 24, 2025

Completed
Last Updated

November 24, 2025

Status Verified

March 1, 2024

Enrollment Period

1 year

First QC Date

November 14, 2025

Last Update Submit

November 19, 2025

Conditions

Keywords

Exercise-induced FatigueElithe AthletesNeurtransmittersMood State

Outcome Measures

Primary Outcomes (6)

  • Serum Testosterone concentration

    Testosterone concentration will be measured in serum using immunoassay. Units: ng/mL.

    Before exercise, immediately after, and 1 hour after recovery

  • Serum Cortisol concentration

    Cortisol concentration will be measured in serum using an immunoassay. Units: ng/mL

    Before exercise, immediately after, and 1 hour after recovery

  • Serum Serotonin concentration

    Serotonin concentration will be measured in serum using an immunoassay. Units: ng/mL

    Before exercise, immediately after, and 1 hour after recovery

  • Serum Gamma-aminobutyric acid (GABA) concentration

    GABA concentration will be measured in serum using an immunoassay. Units: µg/dL

    Before exercise, immediately after, and 1 hour after recovery

  • Serum Tryptophan concentration

    Tryptophan concentration will be measured in serum using an immunoassay. Units: µg/dL

    Before exercise, immediately after, and 1 hour after recovery

  • Profile of Mood States

    Self-reported mood assessed using the Profile of Mood States (POMS); total and subscale scores.

    Before exercise

Secondary Outcomes (2)

  • T:C ratio

    Before exercise, immediately after, and 1 hour after recovery

  • S:D ratio

    Before exercise, immediately after, and 1 hour after recovery

Study Arms (2)

Elite male rowers

Other: Maximal Rowing Test

Elite female rowers

Other: Maximal Rowing Test

Interventions

Participants completed a 2000-meter maximal rowing ergometer test on day 8 following a standardized 7-day high-load training period. The test served as the physiological and psychological stressor used to assess acute fatigue responses.

Elite female rowersElite male rowers

Eligibility Criteria

Age19 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

All participants were recruited and tested at the Central Sports Centre - Olympic Preparation Center (COS OPO) in Wałcz, Poland, during a national team training camp under standardized conditions.

You may qualify if:

  • Aged 19-25 years National-level competitive rower Minimum 5 years of structured rowing training Currently in full training and competition season Completed 7-day standardized high-load training program Provided written informed consent

You may not qualify if:

  • Use of medications or supplements affecting hormonal or neurochemical markers Known endocrine, neurological, or psychiatric disorders Injury or illness interfering with training or testing Incomplete participation in the training camp or testing protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Poznań University of Physical Education

Poznan, Greater Poland Voivodeship, 61-871, Poland

Location

Study Officials

  • Anna Skarpańska-Stejborn, Professor

    Poznań University of Physical Education, Faculty of Sport Sciences in Gorzów Wielkopolski, Poland;

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 14, 2025

First Posted

November 24, 2025

Study Start

March 15, 2024

Primary Completion

March 30, 2025

Study Completion

June 30, 2025

Last Updated

November 24, 2025

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be shared. Data will be used only for internal analysis and dissemination in scientific publications in aggregate form, in accordance with ethical approval.

Locations