Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor

NCT07416487 | Completed

• 1 other identifier: Dr-Zunaira-DGK
• Study Type: interventional
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

There are gaps in the local data regarding the comparative effectiveness of Foley catheter versus misoprostol for induction of labor (IOL). Therefore, the current study was planned with the objective of comparing the mean induction-to-delivery interval of Foley catheter versus misoprostol for IOL in singleton term pregnancy.

Conditions

Labor

Outcome Measures

Primary Outcomes (1)

• Delivery of the fetus

  Induction-to-delivery interval was calculated from the insertion of the Foley catheter or misoprostol until the delivery of the fetus in hours.

  24 hours

Study Arms (2)

Misoprostol Group

EXPERIMENTAL

Women received intravaginal misoprostol 25 μg 4 hours apart, up to a maximum of four doses.

Drug: Misoprostol

Foley Group

EXPERIMENTAL

An intracervical Foley catheter (16 F) was inserted into the patients. The balloon was inflated with 30 mL of sterile normal saline solution and was kept in place until it expelled spontaneously.

Device: Foley catheter

Interventions

Misoprostol DRUG

Women received intravaginal misoprostol 25 μg 4 hours apart, up to a maximum of four doses.

Misoprostol Group

Foley catheter DEVICE

An intracervical Foley catheter (16 F) was inserted into the patients. The balloon was inflated with 30 mL of sterile normal saline solution and was kept in place until it expelled spontaneously.

Foley Group

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Pregnant females
• years
• With a singleton term pregnancy (37-41) weeks
• Parity \< 4
• Vertex presentation (on ultrasound scan)
• Intact membranes (on history and clinical examination)
• Going through labor induction

You may not qualify if:

• With a previous uterine surgery
• Non-reassuring cardiotocography (CTG)
• Oligohydramnios (on ultrasound scan)
• Intrauterine growth restriction (IUGR) (on ultrasound scan)
• Abruptio placenta (on ultrasound scan).

Sponsors & Collaborators

• Muhammad Aamir Latif: lead

Study Sites (1)

D.G. Khan Medical College/Allama Iqbal Teaching Hospital

Dera Ghazi Khan, Punjab Province, 32200, Pakistan

Location

MeSH Terms

Interventions

Misoprostol

Intervention Hierarchy (Ancestors)

Prostaglandins E, Synthetic; Prostaglandins, Synthetic; Prostaglandins; Eicosanoids; Fatty Acids, Unsaturated; Fatty Acids; Lipids; Autacoids; Inflammation Mediators; Biological Factors

Study Officials

• Zunera Sumbal

  D.G. Khan Medical College/Allama Iqbal Teaching Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Research Consultant

Study Record Dates

• First Submitted: February 10, 2026
• First Posted: February 18, 2026
• Study Start: February 1, 2025
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: February 18, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)