NCT07415759

Brief Summary

The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
33mo left

Started Apr 2026

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress5%
Apr 2026Feb 2029

First Submitted

Initial submission to the registry

February 10, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 17, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

April 4, 2026

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 2, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 2, 2029

Last Updated

April 8, 2026

Status Verified

April 1, 2026

Enrollment Period

2.8 years

First QC Date

February 10, 2026

Last Update Submit

April 2, 2026

Conditions

Healthy Subjects

Outcome Measures

Primary Outcomes (9)

  • Conductivity in S/m at the head level in subjects aged 6 to 12 years

    Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years

    Baseline (J0)

  • Conductivity in S/m at the head level in subjects aged 20 to 40 years

    Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years

    Baseline (J0)

  • Conductivity in S/m at the head level in subjects aged 70 and above

    Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above

    Baseline (J0)

  • Conductivity in S/m at the neck level in subjects aged 6 to 12 years

    Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years

    Baseline (J0)

  • Conductivity in S/m at the neck level in subjects aged 20 to 40 years

    Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 20 to 40 years

    Baseline (J0)

  • Conductivity in S/m at the neck level in subjects aged 70 and above

    Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 70 and above

    Baseline (J0)

  • Conductivity in S/m at the torso level in subjects aged 6 to 12 years

    Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 6 to 12 years

    Baseline (J0)

  • Conductivity in S/m at the torso level in subjects aged 20 to 40 years

    Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 20 to 40 years

    Baseline (J0)

  • Conductivity in S/m at the torso level in subjects aged 70 and above

    Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 70 and above

    Baseline (J0)

Study Arms (3)

Children between 6 and 12 years old

EXPERIMENTAL
Device: Magnetic Resonance Imaging (MRI) examination

Adults between 20 and 40 years old

EXPERIMENTAL
Device: Magnetic Resonance Imaging (MRI) examination

Adults aged 70 and above

EXPERIMENTAL
Device: Magnetic Resonance Imaging (MRI) examination

Interventions

Magnetic Resonance Imaging (MRI) examinationDEVICE

MRI examination of the head and neck, and torso for the measurement of electrical properties

Adults aged 70 and aboveAdults between 20 and 40 years oldChildren between 6 and 12 years old

Eligibility Criteria

Age6 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Person aged between 6 and 12, 20 and 40 years or aged 70 years and above
  • Person affiliated with a social security scheme or beneficiary of such a scheme
  • Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form

You may not qualify if:

  • Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device
  • Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters
  • Pregnant woman, woman in labor, or breastfeeding mother
  • Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

CHRU Nancy

Vandœuvre-lès-Nancy, CHRU de Nancy, 54511, France

Location

Institut de Physique Biologique

Strasbourg, 67085, France

Location

MeSH Terms

Interventions

Magnetic Resonance ImagingPhysical Examination

Intervention Hierarchy (Ancestors)

TomographyDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Central Study Contacts

Marc BRAUN, MD, PhD

CONTACT

0383157823m.braun@chru-nancy.fr

Guillaume DROUOT, PhD

CONTACT

0383157666g.drouot@chru-nancy.fr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 10, 2026

First Posted

February 17, 2026

Study Start

April 4, 2026

Primary Completion (Estimated)

February 2, 2029

Study Completion (Estimated)

February 2, 2029

Last Updated

April 8, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations

FR(2)