NCT07414914

Brief Summary

This randomized controlled trial aims to investigate the effects of adding self-myofascial release applied to the plantar fascia and gastrosoleus muscles to an exercise program on foot function, physical performance, and plantar fascia thickness in individuals with type 2 diabetes. Participants aged 30 to 65 years with controlled type 2 diabetes will be randomly allocated to either an exercise-only group or an exercise plus self-myofascial release group. Both groups will complete an eight-week supervised exercise program three times per week. The intervention group will additionally perform self-myofascial release using a foam roller before exercise sessions. Outcomes will include foot function, balance, functional mobility, gait performance, and plantar fascia thickness assessed by ultrasonography before and after the intervention.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable type-2-diabetes

Timeline
Completed

Started Nov 2025

Shorter than P25 for not_applicable type-2-diabetes

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 3, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

February 11, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

February 17, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 4, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 4, 2026

Completed
Last Updated

February 17, 2026

Status Verified

February 1, 2026

Enrollment Period

6 months

First QC Date

February 11, 2026

Last Update Submit

February 11, 2026

Conditions

Keywords

Exercise therapySelf-myofascial releasePhysical performanceFoot functionPlantar fascia

Outcome Measures

Primary Outcomes (1)

  • Foot Function Index (FFI)

    The Foot Function Index will be used to assess pain and disability related to foot function.

    Baseline and 8 weeks

Secondary Outcomes (6)

  • Single-Leg Stance Test (Eyes Open and Eyes Closed)

    Baseline and 8 weeks

  • Timed Up and Go Test (TUG)

    Baseline and 8 weeks

  • Unilateral Heel-Rise Test

    Baseline and 8 weeks

  • Berg Balance Scale (BBS)

    Baseline and 8 weeks

  • 10-Meter Walk Test (Single-Task and Dual-Task)

    Baseline and 8 weeks

  • +1 more secondary outcomes

Study Arms (2)

Exercise Group :8-week supervised exercise program, 3 times per week.

ACTIVE COMPARATOR

8-week supervised strengthening and stretching program performed three times weekly

Behavioral: Exercise Program

Exercise Plus Self-Myofascial Release Group

EXPERIMENTAL

An 8-week supervised strengthening and stretching exercise program performed three times per week combined with self-myofascial release applied to the plantar fascia and gastrosoleus muscles using a foam roller before exercise sessions.

Behavioral: Exercise ProgramOther: Self-Myofascial Release

Interventions

An 8-week supervised strengthening and stretching program performed three times weekly, with advice to perform at least 150 minutes per week of moderate-intensity walking.

Exercise Group :8-week supervised exercise program, 3 times per week.Exercise Plus Self-Myofascial Release Group

Self-myofascial release applied to the plantar fascia and gastrosoleus muscles using a foam roller three times per week for eight weeks before exercise sessions.

Exercise Plus Self-Myofascial Release Group

Eligibility Criteria

Age30 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals aged 30 to 65 years
  • Diagnosed with type 2 diabetes mellitus for at least 1 year
  • Controlled type 2 diabetes mellitus
  • Able to ambulate independently without assistive devices

You may not qualify if:

  • Severe pes planus or pes cavus defined by the Foot Posture Index-6 (FPI-6) (score ≥ +10 or ≤ -5)
  • History of plantar fasciitis
  • Plantar fascia ulceration
  • Peripheral neuropathy
  • Diagnosed peripheral vascular disease
  • History of lower extremity surgery or fracture during last year
  • Rheumatologic or connective tissue disorders affecting soft tissue properties
  • Neurological or diagnosed cognitive disorders
  • Pregnancy
  • Other types of diabetes mellitus
  • Obesity (BMI \> 30 kg/m²)
  • Serious cardiopulmonary disorders, including heart failure, history of myocardial infarction, or severe chronic obstructive pulmonary disease or asthma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bakırçay University Çiğli Regional Education Hospital

Izmir, İzmir, TR-35620, Turkey (Türkiye)

RECRUITING

Related Publications (5)

  • Freire Ribeiro DL, Medeiros FVA, Marinho EBA, Ferreira Junior JB, Bottaro MF, Carmo JC. Effects of myofascial release of the ankle plantar flexors on static postural balance of young men: A randomized clinical trial. J Bodyw Mov Ther. 2021 Oct;28:121-125. doi: 10.1016/j.jbmt.2021.07.034. Epub 2021 Aug 19.

  • Ranbhor AR, Prabhakar AJ, Eapen C. Immediate effect of foam roller on pain and ankle range of motion in patients with plantar fasciitis: A randomized controlled trial. Hong Kong Physiother J. 2021 Jun;41(1):25-33. doi: 10.1142/S1013702521500025. Epub 2020 Oct 8.

  • Kiyono R, Onuma R, Yasaka K, Sato S, Yahata K, Nakamura M. Effects of 5-Week Foam Rolling Intervention on Range of Motion and Muscle Stiffness. J Strength Cond Res. 2022 Jul 1;36(7):1890-1895. doi: 10.1519/JSC.0000000000003757. Epub 2020 Oct 9.

  • Cakici R, Saldiran TC, Kara I, Acik H. Plantar fascia stiffness in patients with type 2 diabetes mellitus: Stiffness effect on fall risk and gait speed. Foot (Edinb). 2023 Sep;56:102020. doi: 10.1016/j.foot.2023.102020. Epub 2023 Mar 17.

  • Konrad A, Nakamura M, Tilp M, Donti O, Behm DG. Foam Rolling Training Effects on Range of Motion: A Systematic Review and Meta-Analysis. Sports Med. 2022 Oct;52(10):2523-2535. doi: 10.1007/s40279-022-01699-8. Epub 2022 May 26.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Sevtap GUNAY UÇURUM, Prof

    Izmir Katip Celebi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

    STUDY DIRECTOR

Central Study Contacts

Sümena HAREKET KARAKAYA, PT

CONTACT

Müge KIRMIZI, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: A Randomized Controlled Trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physiotherapist, MSc student

Study Record Dates

First Submitted

February 11, 2026

First Posted

February 17, 2026

Study Start

November 3, 2025

Primary Completion

May 4, 2026

Study Completion

May 4, 2026

Last Updated

February 17, 2026

Record last verified: 2026-02

Locations