NCT07384819

Brief Summary

This study investigates the temporal dynamics of perception and attention in children with Autism Spectrum Disorder (ASD), focusing on two key phenomena: the Temporal Integration Window (TIW) and the attentional blink. Using eye-tracking, 3- and 5-year-old children with ASD (prototypical or not) will be compared to age-matched neurotypical peers. The investigators hypothesize that children with ASD exhibit shorter TIWs and attentional blinks, reflecting faster perceptual sampling and attentional processing. These characteristics may contribute to sensory hypersensitivity and difficulties in complex, unpredictable environments such as social situations. The protocol includes two experimental tasks.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
228

participants targeted

Target at P75+ for not_applicable

Timeline
27mo left

Started Feb 2026

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress9%
Feb 2026Aug 2028

First Submitted

Initial submission to the registry

January 27, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 3, 2026

Completed
13 days until next milestone

Study Start

First participant enrolled

February 16, 2026

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 16, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 16, 2028

Last Updated

February 5, 2026

Status Verified

February 1, 2026

Enrollment Period

2.5 years

First QC Date

January 27, 2026

Last Update Submit

February 3, 2026

Conditions

Keywords

autismPrototypical autismTemporal Integration WindowAttentional BlinkEye-trackingVisual perceptionInfant development

Outcome Measures

Primary Outcomes (2)

  • Temporal dynamics of perception

    The Temporal Integration Window (TIW) is defined as the shortest interval between two displays that can be integrated into a single percept

    Baseline

  • Temporal dynamics of attention

    The Attentional Blink duration, defined as the minimal delay between two target stimuli that allows detection of both.

    Baseline

Study Arms (6)

Neurotypical 3-year-olds

OTHER

3-year-old children without a neurodevelopmental disorder

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Neurotypical 5-year-olds

OTHER

5-year-old children without a neurodevelopmental disorder

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Prototypical ASD 3-year-olds

EXPERIMENTAL

3-year-old children with a diagnosis of ASD and prototypical characteristics

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Prototypical ASD 5-year-olds

EXPERIMENTAL

5-year-old children with a diagnosis of ASD and prototypical characteristics

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Non-prototypical ASD 3-year-olds

EXPERIMENTAL

3-year-old children with a diagnosis of ASD but not prototypical characteristics

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Non-prototypical ASD 5-year-olds

EXPERIMENTAL

5-year-old children with a diagnosis of ASD but not prototypical characteristics

Behavioral: Temporal Integration Window taskBehavioral: Attentional Blink task

Interventions

The TIW task involves alternating visual displays (integration and segmentation trials) across four inter-stimulus intervals (ISI: 16, 32, 83, 116 ms). This task allows estimation of the participant's perceptual integration threshold.

Neurotypical 3-year-oldsNeurotypical 5-year-oldsNon-prototypical ASD 3-year-oldsNon-prototypical ASD 5-year-oldsPrototypical ASD 3-year-oldsPrototypical ASD 5-year-olds

The Attentional Blink task presents rapid sequences of images (including two targets and distractors), measuring the minimum time delay required for both targets to be detected. Three different T1-T2 intervals are tested.

Neurotypical 3-year-oldsNeurotypical 5-year-oldsNon-prototypical ASD 3-year-oldsNon-prototypical ASD 5-year-oldsPrototypical ASD 3-year-oldsPrototypical ASD 5-year-olds

Eligibility Criteria

Age36 Months - 71 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Children aged 3 or 5 years
  • Either with a diagnosis of Autism Spectrum Disorder (ASD) or typically developing (neurotypical)
  • No intellectual disability (per Mullen, Denver, or psychometric report)
  • Normal or corrected vision and hearing
  • Written informed consent from legal guardians
  • Legal guardians affiliated to a French social security plan
  • For ASD group only : classification as prototypical or non-prototypical based on clinical evaluation

You may not qualify if:

  • Neurological disorder
  • Parental or child refusal to participate
  • For neurotypical children: developmental delay or psychiatric diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Baby lab - Institut des sciences cognitives Marc Jeannerod

Bron, France

Location

CEDA - Le Vinatier

Bron, France

Location

MeSH Terms

Conditions

Autism Spectrum DisorderAutistic Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 27, 2026

First Posted

February 3, 2026

Study Start

February 16, 2026

Primary Completion (Estimated)

August 16, 2028

Study Completion (Estimated)

August 16, 2028

Last Updated

February 5, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

Locations