Improving Frailty in Patients With Stable Ischemic Heart Disease

NCT07373119 | Enrolling By Invitation

• 2 other identifiers: ethics committee 25/198-PAjuts XB
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to improve the frailty in old patients who have a cardiac disease . Researchers will determine the improvement in the instability and the strength along twelve sessions based on guided exercises and mobility techniques made by physiotherapists. Research team will also evaluate the medications and diet, as well as laboratory and clinical tests.

Conditions

Coronary Heart Disease

Keywords

frailty; coronary heart disease; elderly

Outcome Measures

Primary Outcomes (1)

• Short Physical Performance Battery (SPPB) components (balance, gait speed, chair rise)

  Improvement in baseline values: each of the three component scores \<= 4 points, and tests consists of: balance test, Gait speed and chair-stand tests. Maximum possible is 12 points and under 10 points means frailty

  From enrollment to the end of treatment ending after 12 weeks.

Secondary Outcomes (1)

• Euroqol5D Goldberg Anxiety and Depression Scale Number of falls throughout the study Major Cardiovascular events Adherence to the program

  from the baseline to 12 weeks of intervention

Study Arms (1)

Patients with stable coronary heart disease

EXPERIMENTAL

older than 70 years, idependents in ADL

Other: physiotherapy

Interventions

physiotherapy OTHER

Primary care based physiotherapy groups

Patients with stable coronary heart disease

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Age ≥ 70 years
• Diagnosis of coronary artery disease (International Classification Diseases (ICD)-10 I20-I25)
• Canadian Cardiovascular Society Class I

You may not qualify if:

• Inability or refusal to provide informed consent (advanced dementia, severe psychiatric illness)
• Inability to perform protocol procedures
• Severe mobility-limiting conditions (Parkinson's disease, progressive neurological disorders, disabling joint disease)
• Recent (\<6 months) unstable angina, myocardial infarction, coronary revascularization or angioplasty
• Deep venous thrombosis or pulmonary embolism in the last 6 months
• Recent stroke (\<6 months)
• Heart failure in New York Heart Assocaition functional status (NYHA) III-IV
• Left ventricular ejection fraction \< 50%
• Symptomatic valvular heart disease

Sponsors & Collaborators

• Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina: lead

Study Sites (1)

Primary Care Centers

Barcelona, Select..., 08007, Spain

Location

MeSH Terms

Conditions

Coronary Disease; Frailty

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Therapeutics; Rehabilitation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: It is an experimental study before-after based on a program of 12 sessions of physiotherapy in primary care setting

Study Record Dates

• First Submitted: December 2, 2025
• First Posted: January 28, 2026
• Study Start: October 1, 2025
• Primary Completion: December 30, 2025
• Study Completion (Estimated): December 31, 2026
• Last Updated: January 28, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)