Implementation of AIP Services for Older Adults With AD

NCT07361601 | Not Yet Recruiting DMC

• 1 other identifier: R01AG091323-01
• Study Type: observational
• Target: 285
• Locations: 1 country
• Sites: 1

Brief Summary

This study will longitudinally follow a cohort of older adults to better understand how decisions about aging in place or transitioning to long-term care-and the implementation of those decisions-are influenced by age-related changes (e.g., cognition, health literacy, chronic conditions) and social supports (e.g., caregivers).

Conditions

Alzheimer Disease; Mild Cognitive Impairment

Keywords

Aging in place; Long term care planning

Outcome Measures

Primary Outcomes (1)

• Rate of participant long term care planning for Alzheimer's Dementia/Memory Loss

  Participants are asked "If you developed Alzheimer's or memory loss and could no longer live independently in your home, have you decided what your living preferences (e.g. stay in own home, retirement/long term care community) would be?" Decision-making is measured as a binary ('yes', 'no') outcome at each time-point. Will report % of participants who indicated "YES", that they have decided on their living preferences. Frequencies given for 108 month timepoint per primary outcome analysis.

  Assessed every 6 months, 108 months reported

Secondary Outcomes (9)

• Rate of participant planning for in-home care in the event of Alzheimer's Disease/Memory Loss

  Assessed every 6 months, 108 months reported

• Rate of participant planning for memory care in the event of Alzheimer's Disease/Memory Loss

  Assessed every 6 months, 108 months reported

• Rate of participant planning for a hospitalization requiring rehabilitation outside the home

  Assessed every 6 months, 108 months reported

• Rate of participant planning for a hospitalization requiring in-home care

  Assessed every 6 months, 108 months reported

• Rate of participant decision-making contemplation: Alzheimer's Dementia/Memory Loss (ADML)

  Assessed every 6 months, 108 months reported

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of a cohort of older adults who are currently enrolled in the longitudinal study, R01AG058777. Older adults as well as their caregivers, where appropriate, are being followed over time to assess decision-making and planning related to aging in place and potential transitions to long-term care. The cohort includes individuals with varying levels of cognitive function, health status, chronic conditions, and social support, as well as diverse living environments (e.g., rural and urban settings, different types of housing). Participants will continue to be followed prospectively.

You may qualify if:

• Active participant in the 'Decision Making and Implementation of Aging-in-Place/Long Term Care Plans among Older Adults' \[R01AG058777\] study;
• Age 65 years or older (older adult); age 18 years or older (caregiver)
• Speak English; and
• Pass UBACC (University of California, San Diego Brief Assessment of Capacity to Consent) cognitive assessment
• Age 18 years or older;
• Speak English;
• Currently assist enrolled, older adult study participant with activities such as managing their health, and/or household activities (i.e., taking them to the doctor, housekeeping, meal prep, medication reminders); and
• Pass UBACC (University of California, San Diego Brief Assessment of Capacity to Consent) cognitive assessment

Sponsors & Collaborators

• Northwestern University: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

Location

MeSH Terms

Conditions

Alzheimer Disease; Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders; Cognition Disorders

Study Officials

• Lee A Lindquist, MD MPH MBA

  Northwestern University Feinberg School of Medicine

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Vanessa Ramirez-Zohfeld, MPH

CONTACT

312-503-3916; vanessa-ramirez-0@northwestern.edu

Charlie Olvera, MA, MS

CONTACT

Charlie.Olvera@Northwestern.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Medicine, Section Chief - Geriatrics

Study Record Dates

• First Submitted: January 21, 2026
• First Posted: January 23, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): March 31, 2030
• Study Completion (Estimated): December 31, 2031
• Last Updated: January 23, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)