NCT07358507

Brief Summary

The purpose of this study is to learn if adding specific "nerve gliding" exercises to a standard physical therapy program helps reduce pain and improve hand function in people with ulnar-sided (pinky side) wrist pain. Participants who have had wrist pain for at least 3 months will be randomly assigned to one of two groups. Both groups will receive a standard treatment program that includes patient education, activity modification, massage, and ice application. One group will also perform specific nerve gliding exercises for the ulnar nerve. Researchers will evaulate pain level, hand function, strength, weight-bearing tolerance, and joint position sense at the beginning and after 4 weeks of treatment to see if the exercises provide extra benefit. The study treatment period lasts for 4 weeks.

Trial Health

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Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 23, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 14, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 22, 2026

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2026

Completed
Last Updated

January 22, 2026

Status Verified

January 1, 2026

Enrollment Period

3 months

First QC Date

January 14, 2026

Last Update Submit

January 14, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain Level

    Pain level will be evaluated using the Visual Analog Scale (VAS) for pain at rest, during activity, and at night.

    From enrollment to the end of treatment at 4 weeks

Secondary Outcomes (5)

  • Wrist Function

    Baseline and 4 weeks.

  • Grip Strength

    Baseline and 4 weeks

  • Wrist Strength

    Baseline and 4 weeks

  • Weight Bearing Tolerance

    Baseline and 4 weeks

  • Joint Position Sense

    Baseline and 4 weeks.

Study Arms (2)

Control Group

ACTIVE COMPARATOR

Participants in this group will receive standard treatment consisting of patient education, activity modification, massage, and ice application for 4 weeks.

Other: Conventional Physiotherapy

Mobilization Group

EXPERIMENTAL

Participants in this group will receive standard treatment including patient education, activity modification, massage, and ice application. In addition, they will perform ulnar nerve gliding exercises for 4 weeks.

Other: Ulnar Nerve Gliding ExercisesOther: Conventional Physiotherapy

Interventions

Ulnar nerve gliding exercises will be performed twice a week in the clinic for 4 weeks. Participants will also perform these exercises as a home program 3 times daily.

Mobilization Group

Includes patient education, activity modification, classic massage along the ulnar nerve trace, and ice application (10-12 minutes) at the end of each session.

Control GroupMobilization Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Being over 18 years of age.
  • History of ulnar-sided wrist pain lasting for at least 3 months.
  • Diagnosis of ulnar-sided wrist pain confirmed by a hand surgeon, which may include: fractures or dislocations of the 4th and 5th metacarpals, hamate, triquetrum, lunate, pisiform, distal ulna, or distal radius; Lunotriquetral ligament tears; Kienböck's disease; Ulnar impaction syndrome; Triangular Fibrocartilage Complex (TFCC) injury; carpal instabilities; DRUJ instability; pisotriquetral arthritis; DRUJ arthritis; extensor carpi ulnaris (ECU) tendon subluxation; or tendinitis of the ECU, extensor digiti minimi, and flexor carpi ulnaris.
  • Adequate cognitive level (scoring 22 or above on the Montreal Cognitive Assessment scale).

You may not qualify if:

  • Presence of other diseases involving the hand and wrist (e.g., carpal tunnel syndrome, Dupuytren's disease).
  • History of traumatic injury to the hand, wrist, and/or forearm within the last 3 months.
  • History of surgery on the hand, wrist, and/or forearm within the last 6 months.
  • Currently receiving treatment for hand and wrist problems.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi University Health Sciences Faculty Physiotherapy and Rehabilitation Department

Ankara, Turkey (Türkiye)

RECRUITING

Central Study Contacts

Ceren Zorluogullari

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master's Student

Study Record Dates

First Submitted

January 14, 2026

First Posted

January 22, 2026

Study Start

October 23, 2025

Primary Completion

February 1, 2026

Study Completion

February 1, 2026

Last Updated

January 22, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations