All-on-X Stackable Guides for Maxillary Terminal Dentition

NCT07353619 | Recruiting DMC

• 1 other identifier: ADMNF-002026
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading. Implant survival and peri-implant outcomes will be assessed over a 2-year follow-up, with regression analysis will be used to investigate the influence of surgical and prosthetic variables, including basal seating guide design.

Conditions

Bone Loss

Outcome Measures

Primary Outcomes (1)

• Implant Survival Rate

  Implant survival was defined as the presence of the implant in situ without removal for any reason, including biological or mechanical failure. Survival was assessed clinically and radiographically following implant placement and immediate loading.

  6 months after implant placement

Interventions

Maxillary All-on-X implant rehabilitation using a fully digital stackable guided surgery workflow with immediate loading. OTHER

Patients underwent maxillary full-arch implant rehabilitation using an All-on-X concept performed with a fully digital stackable guided surgery workflow and an immediate loading protocol. Implant placement was planned prosthetically using three-dimensional imaging and digital planning software. Stackable surgical guides were used to facilitate guided bone reduction when indicated and fully guided implant placement. Six implants were placed in the maxillary arch under local anesthesia following a standardized surgical protocol. Implants achieving adequate primary stability were immediately restored with a screw-retained provisional fixed prosthesis supported by multi-unit abutments. Patients were followed according to a predefined clinical and radiographic protocol for outcome assessment.

Also known as: Stackable guided implant surgery

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of adult patients with terminal maxillary dentition who underwent rehabilitation with a maxillary All-on-6 implant-supported complete fixed dental prosthesis using a fully digital stackable guided surgery workflow and immediate loading protocol. Patients included had complete clinical and radiographic records available and were followed for a minimum of 2 years. Prosthetic designs were limited to FP-1 or FP-2 according to Misch classification. Patients with uncontrolled systemic conditions, previous head and neck radiotherapy, untreated infections, or requiring simultaneous bone grafting were excluded.

You may qualify if:

• Adult patients presenting with terminal dentition of the maxillary arch
• Rehabilitation with a maxillary All-on-6 implant-supported complete fixed dental prosthesis
• Treatment performed using a fully digital stackable guided surgery workflow
• Immediate loading with a provisional fixed prosthesis
• Availability of complete clinical and radiographic records
• Minimum follow-up period of 2 years
• Prosthetic design classified as (Fixed prosthesis) FP-1 or FP-2 according to Misch classification

You may not qualify if:

• Uncontrolled systemic conditions contraindicating implant surgery
• History of head and neck radiotherapy
• Presence of untreated periodontal or peri-implant infection at the time of surgery
• Incomplete or missing clinical or radiographic records
• Cases requiring simultaneous bone grafting procedures
• Severe maxillary atrophy (Cawood and Howell Class III-V)
• Cases requiring FP-3 prosthetic design
• Rehabilitation performed without guided surgery or without immediate loading

Sponsors & Collaborators

• Menoufia University: lead
• Mansoura University: collaborator

Study Sites (1)

Faculty of Dentistry

Shibīn al Kawm, Menoufia, Egypt

RECRUITING

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Mohammed El-Sawy, PhD

  Menoufia University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohammed El-Sawy, PhD

CONTACT

00201061314522; Dr_sawy@windowslive.com

Mohammed T. Khater, PhD

CONTACT

00201003854552; MohamedKhaterdentalsmile1234@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor and principle investigator

Study Record Dates

• First Submitted: January 8, 2026
• First Posted: January 20, 2026
• Study Start: January 1, 2024
• Primary Completion: March 1, 2026
• Study Completion: May 1, 2026
• Last Updated: January 20, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)