NCT06693921

Brief Summary

n the current study, AI-assisted 3D ridge augmentation of combined vertical and horizontal deficient ridges utilizing allogenic dentin block versus allogenic dentin shell graft will be assessed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2024

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 15, 2024

Completed
2 days until next milestone

Study Start

First participant enrolled

November 17, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 19, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2025

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2025

Completed
Last Updated

January 12, 2026

Status Verified

January 1, 2026

Enrollment Period

1 year

First QC Date

November 15, 2024

Last Update Submit

January 9, 2026

Conditions

Bone Loss

Keywords

deficient ridgesArtifitial intelligenceallograftridge reconstruction

Outcome Measures

Primary Outcomes (1)

  • Horizontal buccolingual ridge width

    Measuring the buccolingual width of the ridge will be carried out by calculating the distance between the outer boundaries of the palatal and facial bony plates horizontally at a distance 2 mms away from the implant shoulder apically using CBCT.

    12 months

Secondary Outcomes (2)

  • Facial marginal bone level

    12 months

  • Peri-implant bone density

    12 months

Study Arms (2)

allogenic dentin block

EXPERIMENTAL

Participants will receive allogenic dentin block for reconstruction of combined vertical and horizontal ridge defects with simultaneous implant placement in the maxillary esthetic zone.

Procedure: AI/guided block graft

allogenic dentin shell

EXPERIMENTAL

Participants will receive allogenic dentin shell for reconstruction of combined vertical and horizontal ridge defects with simultaneous implant placement in the maxillary esthetic zone.

Procedure: AI/guided shell graft

Interventions

AI/guided shell graftPROCEDURE

The allo-dentin shell graft will be prepared by placing a dentin shell from extracted teeth in the trim template and trimming with round burs to the planned dimension under the guidance of the template

allogenic dentin shell
AI/guided block graftPROCEDURE

The allo-dentin tooth graft will be prepared by placing a dentin block from extracted teeth in the trim template and trimming with round burs to the planned dimension under the guidance of the template.

allogenic dentin block

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Insufficient vertical and horizontal bone contour for dental implant placement in the maxillary esthetic zone.
  • Volunteer for participating alveolar bone augmentation by allo-dentin graft technique.
  • Absence of any complicating systemic condition that may contraindicate surgical procedures.
  • Adequate oral hygiene.

You may not qualify if:

  • Uncontrolled systematic disorders
  • diabetes mellitus
  • uncontrolled periodontal disease
  • history of head and neck radiotherapy
  • pregnancy
  • noncompliant patients
  • uncooperative individuals
  • those unable to attend the study follow-up appointments

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Kafrelsheikh University

Kafr ash Shaykh, 42524, Egypt

Location

Walid Elamrousy

Kafr ash Shaykh, 76130, Egypt

Location

Related Publications (1)

  • Elraee L, Abdel Gaber HK, Elsayed HH, Adel-Khattab D. Autogenous dentin block versus bone block for horizontal alveolar ridge augmentation and staged implant placement: A randomized controlled clinical trial including histologic assessment. Clin Oral Implants Res. 2022 Jul;33(7):723-734. doi: 10.1111/clr.13936. Epub 2022 May 13.

    PMID: 35509125BACKGROUND

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
single blinded only the outcome assessor is masked
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of periodontology, faculty of oral and dental medicine

Study Record Dates

First Submitted

November 15, 2024

First Posted

November 19, 2024

Study Start

November 17, 2024

Primary Completion

November 20, 2025

Study Completion

November 30, 2025

Last Updated

January 12, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

data will not be shared

Locations

EG(2)