Ultrasound or Whole Body Vibration on Knee Motion and Function in CP

NCT07351292 | Completed DMC

• 1 other identifier: P.T.REC/012/006029
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study compared the efficacy of therapeutic ultrasound (US) and whole-body vibration (WBV) as adjuncts to a standardized passive stretching regimen on improving knee joint range of motion (ROM) and functional capacity in children with hemiplegic cerebral palsy (HCP).

Conditions

Cerebral Palsy (CP)

Keywords

Ultrasound; whole-body vibration; knee range of motion; functional ability; children; hemiplegia; cerebral palsy

Outcome Measures

Primary Outcomes (2)

• Active Knee Extension Range of Motion (ROM)

  Measured using an Absolute + Axis™ Digital Goniometer. With the child supine and pelvis stabilized, the goniometer axis was aligned with the lateral femoral condyle. The stationary arm was aligned with the greater trochanter, and the moving arm with the lateral malleolus. The child was instructed to actively extend the knee as far as possible, and the angle was recorded. Three measurements were taken, and the average was used for analysis

  12 weeks

• 2. Gross Motor Function

  Assessed using the Gross Motor Function Measure-88 (GMFM-88), a validated observational tool for children with CP. A blinded assessor, not involved in the intervention, scored the children's performance. The Gross Motor Functional Measurement-88 used to measure function. The GMFM is a standardized observational instrument designed and validated to measure change in gross motor function over time in children with cerebral palsy. The scoring key is meant to be a general guideline. However, most of the items have specific descriptors for each score. It is imperative that the guidelines contained in the manual be used for scoring each item. SCORING KEY 0 = does not initiate 1. = initiates 2. = partially completes 3. = completes

  12 weeks

Study Arms (2)

ultrasound group

EXPERIMENTAL

received therapeutic ultrasound prior to stretching

Device: ultrasound

whole body vibration group

EXPERIMENTAL

performed exercises on a vibrating platform before stretching

Device: whole body vibration

Interventions

ultrasound DEVICE

Received continuous ultrasound (1 MHz, 1.0 W/cm², 5 min per hamstring) using a Chattanooga Intelect Mobile 2 unit with a medium-sized transducer head and coupling gel

ultrasound group

whole body vibration DEVICE

Performed exercises on a Power Plate Pro 5 vibration platform. Parameters were set to a frequency of 20 Hz and a fixed amplitude of 2 mm (peak-to-peak displacement). The child maintained a semi-squat posture (approximately 30 knee flexion) for two 5-minute bouts separated by a 1-minute rest.

whole body vibration group

Eligibility Criteria

• Age: 4 Years - 6 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• age from 4-6 years
• knee flexion deformity due to hamstring tightness
• Gross Motor Function Classification System (GMFCS) levels I or II
• spasticity grade of 1 or 2 on the modified Ashworth Scale

You may not qualify if:

• other causes of knee flexion deformity
• previous orthopedic knee surgery
• significant visual, auditory, or perceptual deficits
• uncontrolled seizures; or acute illness

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo university

Cairo, 11432, Egypt

Location

MeSH Terms

Conditions

Cerebral Palsy; Hemiplegia

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• mostafa S ali, PhD

  associate professor for pediatrics

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: Masking Description
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor

Model Details: Model Description

Study Record Dates

• First Submitted: January 10, 2026
• First Posted: January 20, 2026
• Study Start: March 6, 2025
• Primary Completion: April 30, 2025
• Study Completion: August 12, 2025
• Last Updated: January 21, 2026

Record last verified: 2026-01

Locations

EG (1)