NCT07350434

Brief Summary

Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished : Nerve tensioning and nerve flossing. They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the position that should be used. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
2mo left

Started Feb 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress64%
Feb 2026Jun 2026

First Submitted

Initial submission to the registry

January 9, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 20, 2026

Completed
12 days until next milestone

Study Start

First participant enrolled

February 1, 2026

Completed
9 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 10, 2026

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Expected
Last Updated

April 28, 2026

Status Verified

April 1, 2026

Enrollment Period

9 days

First QC Date

January 9, 2026

Last Update Submit

April 27, 2026

Conditions

Keywords

stretchingstiffnessnervemuscleflexibilityhip

Outcome Measures

Primary Outcomes (1)

  • Nerve shear wave velocity using elastography in neutral position

    Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was neutral (alignment between the lower limb and the trunk).

    Before the intervention and at the end (immediately after) the intervention

Secondary Outcomes (10)

  • Nerve shear wave velocity using elastography in experimental position

    Before the intervention and at the end (immediately after) the intervention

  • Muscle shear wave velocity using elastography in neutral position

    Before the intervention and at the end (immediately after) the intervention

  • Muscle shear wave velocity using elastography in the experimental position

    Before the intervention and at the end (immediately after) the intervention

  • Hamstring force

    Before the intervention and at the end (immediately after) the intervention

  • Biceps femoris electromyographic activity

    Before the intervention and at the end (immediately after) the intervention

  • +5 more secondary outcomes

Study Arms (6)

No intervention (neutral)

NO INTERVENTION

No intervention with measurements in neutral position

No intervention (adduction)

NO INTERVENTION

No intervention with measurements in adduction position

No intervention (abduction)

NO INTERVENTION

No intervention with measurements in abduction position

Neurodynamic (neutral)

ACTIVE COMPARATOR

The hip was positioned neutral (alignment between the lower limb and the trunk).

Other: Maximal neurodynamic flossing

Neurodynamic (adduction)

EXPERIMENTAL

The hip was positioned in adduction and the neurodynamic stretch was applied.

Other: Maximal neurodynamic flossing

Neurodynamic (abduction)

EXPERIMENTAL

The hip was positioned in abduction and the neurodynamic stretch was applied.

Other: Maximal neurodynamic flossing

Interventions

Neurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain. During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues. Flossing is the alternation of these movements every 2 seconds.

Neurodynamic (abduction)Neurodynamic (adduction)Neurodynamic (neutral)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • healthy
  • physical active
  • no injuries (lower limb or back pain) in the past 3 months

You may not qualify if:

  • Specific lower limb (hamstring) injuries in the past 2 years
  • Not restraining activity 24h before participation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universite Bourgogne Europe - faculty of sports sciences

Dijon, France

RECRUITING

Study Officials

  • Nicolas Babault

    universite bourgogne europe

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof

Study Record Dates

First Submitted

January 9, 2026

First Posted

January 20, 2026

Study Start

February 1, 2026

Primary Completion

February 10, 2026

Study Completion (Estimated)

June 30, 2026

Last Updated

April 28, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

data freely available in online websites

Locations