Effect of Acute Exercise on Sensory and Hedonic Responses to a Fixed Meal in Adolescents With Obesity

NCT06017440 | Completed

• 2 other identifiers: RBHP 2023 BOIRIE 32023-A00808-37
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

While long considered independently, energy expenditure and energy intake have been shown to interact. Fot the last 20 years, the litterature has been describing tyhe effects of an acute bout of exercise on subsequent energy intake and appetitive responses, indicating a potenital anorexigenic effect of intensive exercise in adolescents with obesity. These studies suggest a decrease in hunger, redcued satiety and modified food reward responses. These results remain however obtained in studies using post exercise ad libitum test meals and this nature of the meal might ahve impact these responses. The present work tends to assess the effect of acute exercise on subsequent appetite and food reward responses to a fixed meal, in adolescents with obesity.

Conditions

CONTROL Condition; Exercise

Outcome Measures

Primary Outcomes (3)

• APPETITE FEELINGS

  appetite sensation will be assessed using visual analog scales

  immediately after lunch

• FOOD reward

  food reward will be assessed using the leeds food preference questionnaire

  at lunch time

• Energy intake

  energy intake will be assessed ad libitum at the following diner

  at lunch time

Study Arms (1)

adolescents with obesity

EXPERIMENTAL

There is only one arm as this is an acute randomized study comparing two differents conditions within the same sample of participants.

Behavioral: EXERCISE; Behavioral: CONTROL

Interventions

EXERCISE BEHAVIORAL

Participants will receive at 08:00 am a calibrated breakfast of 500kcal. They should not perform physical exercise during the day. They will be asked at 11 a.m. to cycle for 30 minutes at 65% of the maximal capacities and their energy expenditure will be measured by indirect calorimetry. At 11 a.m., teenagers will receive a calibrated meal of 800 kcal respecting the nutritional recommendations for this age. Questionnaires on feelings of hunger will be distributed to them at regular intervals. They will also be asked to complete a 10-minute computer exercise to assess their relationship to food before and after lunch (LFPQ. Leeds Food Preference Questionnaire, Liking/ wanting). Finally, from 60 minutes after the midday test meal, teenagers will have access to an ad libitum buffet for one hour.

adolescents with obesity

CONTROL BEHAVIORAL

Teenagers should not perform any physical activity during the day and they will be asked to stay at 11 a.m., for 30 minutes, resting in a semi-supine position.

adolescents with obesity

Eligibility Criteria

• Age: 11 Years - 16 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Subjects aged 11 to 16 years (inclusive limits), maturation stage 3-5 according to the Tanner classification, with obesity defined by a body mass index (BMI) greater than the 97th percentile according to national curves (Roland- Cachera et al., 1991).
• Adolescent who has signed the information and consent form and whose holders of parental authority have signed the information and consent form
• Person subject to a Social Security scheme

You may not qualify if:

• Medical or surgical history deemed by the investigator to be incompatible with the study
• Presence of diabetes, and any other pathology limiting the application of one or the other strategy to the trial.
• Taking medications that may interfere with the results of the study
• Subjects with cardiovascular problems, here we are talking about subjects with a history of cardiovascular and/or neurovascular pathology, as well as subjects presenting cardiovascular and/or neurovascular risk factors (excluding obesity/ overweight).
• Surgical intervention in the previous 3 months.
• Consumption of tobacco or alcohol.
• Special diet.
• Participation in regular and intense physical and sports activities for more than two hours per week.
• Teenagers whose parents are under guardianship, curatorship, safeguard of justice or not subject to a social security system
• Refusal to sign the information and consent notice
• Pregnant or breastfeeding adolescents on declarative

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead

Study Sites (1)

CHU de Clermont-Ferrand

Clermont-Ferrand, France

Location

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Yves Boirie

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 13, 2023
• First Posted: August 30, 2023
• Study Start: July 1, 2023
• Primary Completion: September 17, 2023
• Study Completion: October 17, 2023
• Last Updated: October 18, 2023

Record last verified: 2023-10

Locations

FR (1)