Mining the Gut Microbiota of Adults for Health-relevant Microbial Signatures.

NCT07344545 | Completed

• 1 other identifier: Zhujiang-Huzhou
• Study Type: observational
• Target: 1,530
• Locations: 1 country
• Sites: 1

Brief Summary

Mining the gut microbiota of adults for health-relevant microbial signatures.

Conditions

Adult

Outcome Measures

Primary Outcomes (1)

• Identification of Health-Relevant Signatures in Adults

  Primary Outcome Measure 1)Change in standard laboratory parameters from baseline:Changes in routine laboratory parameters measured in blood, urine, and stool samples, including complete blood count and standard serum biochemistry panels.Unit of Measure: Various laboratory units (e.g., g/L, U/L, mmol/L); 2) Change in anthropometric measurements from baseline: Anthropometric measurements including body weight (kg), height (m), and body mass index (BMI, kg/m²).Unit of Measure:kg, m, kg/m²; 3) Alcohol consumption status: Alcohol consumption status assessed by self- report, categorized as current drinker or non-drinker at enrollment.Unit of Measure:Categorical (yes/no); 4) Hospital Anxiety and Depression Scale (HADS) scores: Anxiety and depression symptom severity assessed using the Hospital Anxiety and Depression Scale, including anxiety and depression subscale scores.Unit of Measure:Score on a standardized scale.

  Baseline

Study Arms (1)

adult volunteers

The study population consists of 1,530 middle-aged and elderly volunteers from the same community who underwent comprehensive health examinations at Huzhou Central Hospital . All participants completed a multi-dimensional assessment including biospecimen collection, physical/imaging examinations, and psychometric evaluations.

Other: Observational, non-interventional study.

Interventions

Observational, non-interventional study. OTHER

Observational, non-interventional study.

adult volunteers

Eligibility Criteria

• Age: 30 Years - 95 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Meet eligibility criteria

You may qualify if:

• Community-dwelling adults aged 30 to 95 years.
• Individuals who underwent an annual health examination at the Health Management Center of Huzhou Central Hospital during the specified time period.
• Ability to comprehend the study content and voluntarily provide signed informed consent.
• Willingness and ability to provide the required biospecimens (blood, urine, stool).

You may not qualify if:

• Concurrent participation in another interventional clinical trial that is likely to interfere with the results of this study.
• Voluntary withdrawal from the study.

Sponsors & Collaborators

• Zhujiang Hospital: lead
• Huzhou Central Hospital: collaborator

Study Sites (1)

Zhujiang Hospital of Southern Medical University

Guangzhou, Guangdong, 510000, China

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Department of Laboratory Medicine

Study Record Dates

• First Submitted: December 3, 2025
• First Posted: January 15, 2026
• Study Start: August 15, 2021
• Primary Completion: August 30, 2021
• Study Completion: September 29, 2021
• Last Updated: January 15, 2026

Record last verified: 2025-12

Locations

CN (1)