Ultrasound-Based Airway Assessment for Predicting Difficult Intubation in Adult Female Patients

NCT07343557 | Completed

• 1 other identifier: ADN-USG-AIRWAY-2025
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the ability of selected ultrasonographic airway measurements to predict difficult intubation in adult female patients undergoing elective surgery. Pre-induction airway ultrasonography will be performed to measure tongue thickness and anterior neck soft tissue-related parameters. These measurements will be compared with laryngoscopic findings during direct laryngoscopy. The results of this study may help identify practical and reliable ultrasound-based markers for preoperative airway assessment and improve patient safety.

Conditions

Difficult Intubation; Airway Assessment

Keywords

Airway Ultrasound; Tongue Thickness; Difficult Airway

Outcome Measures

Primary Outcomes (1)

• Incidence of Difficult Intubation

  Difficult intubation defined as Cormack-Lehane grade III or IV and/or the need for additional airway devices or techniques during tracheal intubation.

  Perioperative

Secondary Outcomes (4)

• Ultrasonographic Measurement of Tongue Thickness

  Preoperative assessment

• Ultrasonographic Measurement of Skin-to-Hyoid Bone Distance

  Preoperative assessment

• Ultrasonographic Measurement of Skin-to-Epiglottis Distance

  Preoperative assessment

• Ultrasonographic Measurement of Distance from Skin to Anterior Commissure of the Vocal Cords

  Preoperative assessment

Study Arms (1)

Airway Ultrasound Assessment Cohort

Adult female patients undergoing elective surgery in whom preoperative airway ultrasonography was performed for observational assessment of airway anatomy. No intervention was assigned as part of the study.

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult female patients aged 18-65 years undergoing elective surgery under general anesthesia at a tertiary care hospital. Participants were non-pregnant and scheduled for non-emergency procedures.

You may qualify if:

• Female patients aged 18-65 years
• American Society of Anesthesiologists (ASA) physical status I-III physical status I-III
• Scheduled for elective surgery under general anesthesia requiring tracheal intubation
• Ability to provide informed consent

You may not qualify if:

• Body mass index ≥30 kg/m²
• Known history of difficult intubation
• Anatomical airway abnormalities or head and neck pathology
• Pregnancy
• Emergency surgery

Sponsors & Collaborators

• Adana City Training and Research Hospital: lead

Study Sites (1)

Adana City Training and Research Hospital

Adana, Adana, 010650, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiologist

Study Record Dates

• First Submitted: December 29, 2025
• First Posted: January 15, 2026
• Study Start: May 15, 2025
• Primary Completion: December 15, 2025
• Study Completion: December 15, 2025
• Last Updated: January 15, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)