NCT07329673

Brief Summary

The purpose of this study is to evaluate QbMobile's ability to collect objective data to identify specific symptom profiles in differential diagnoses (ASD, MDD, Bipolar Disorder and Anxiety Disorder) that are common with ADHD.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
6mo left

Started Jan 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress42%
Jan 2026Nov 2026

First Submitted

Initial submission to the registry

December 11, 2025

Completed
21 days until next milestone

Study Start

First participant enrolled

January 1, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 9, 2026

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Last Updated

May 6, 2026

Status Verified

May 1, 2026

Enrollment Period

10 months

First QC Date

December 11, 2025

Last Update Submit

May 4, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Identification of QbMobile Domain Profiles Using SD-Scores and Total Score (0-100)

    QbMobile is a software application that measures cognitive performance and activity levels, including attention, impulsivity, activity, and movement patterns. The study will identify statistically distinct QbMobile domain profiles for each diagnostic group (ASD, MDD, Bipolar Disorder, Anxiety Disorder) using domain SD-scores and the QbMobile Total Score (0-100). (Component metrics are listed as secondary outcomes to meet single-measure reporting requirements.)

    Two QbMobile tests: at the clinic (Visit 1) and remotely the following day (Visit 2)

Secondary Outcomes (10)

  • QbMobile Domain SD-Scores (Attention, Impulsivity, Activity, Movement) - Group Differences

    Two QbMobile tests: at the clinic (Visit 1) and remotely the following day (Visit 2)

  • QbMobile Total Score (0-100) - Group Differences

    Two QbMobile tests: at the clinic (Visit 1) and remotely the following day (Visit 2)

  • Classification Accuracy Using QbMobile Domain SD-Scores

    Two QbMobile tests: at the clinic (Visit 1) and remotely the following day (Visit 2)

  • Classification Accuracy Using QbMobile Total Score (0-100)

    QbMobile completed at Visit 1 (Day 1) and Visit 2 (Day 2)

  • Comparison of QbMobile Domain SD-Scores with Normative Dataset

    Two QbMobile tests: at the clinic (Visit 1) and remotely the following day (Visit 2).

  • +5 more secondary outcomes

Study Arms (6)

ASD

Eligible participants being referred for their initial assessment or have a diagnosis of ASD but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

Bipolar disorder

Eligible participants being referred for their initial assessment or have a diagnosis of Bipolar Disorder but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

MDD

Eligible participants being referred for their initial assessment or have a diagnosis of MDD but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

Separation Anxiety Disorder

Eligible participants being referred for their initial assessment or have a diagnosis of Separation Anxiety Disorder but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

Social Anxiety Disorder

Eligible participants being referred for their initial assessment or have a diagnosis of Social Anxiety Disorder but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

Generalized Anxiety Disorder

Eligible participants being referred for their initial assessment or have a diagnosis of Generalized Anxiety Disorder but currently not receiving treatment who are attending a clinic visit at study sites will be approached by a clinic research staff about the study or contacted prior to their appointment.

Device: Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)

Interventions

Participants will complete two non-invasive, 10-minute digital tests using the QbMobile Investigational Device-one at the clinic and one at home the following day. The tests objectively measure cognitive performance and activity levels and will not influence clinical diagnosis or treatment in this study.

ASDBipolar disorderGeneralized Anxiety DisorderMDDSeparation Anxiety DisorderSocial Anxiety Disorder

Eligibility Criteria

Age6 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Potential study participants who meet the eligibility criteria will be identified through referrals and recruitment efforts at the participating study sites.

You may qualify if:

  • Provide written informed consent (including parent/legal guardians consent when this is required for individuals under 18 years old and assent as is required based on the age of participant) for QbMobile;
  • Aged \> 6 years and \< 60 years old;
  • Referred for an initial assessment for ASD, MDD, Bipolar Disorder or Anxiety Disorder (Separation Anxiety Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder (GAD)) or has a prior diagnosis of one of the included disorders but is not currently receiving treatment;
  • Meets DSM-5 or ICD-11 criteria for a primary diagnosis of ASD, MDD, Bipolar Disorder or Anxiety Disorder per sites standard clinical procedures;
  • Have adequate sensory and physical ability to complete QbMobile;
  • Possess or have access to an iPhone model that supports QbMobile.

You may not qualify if:

  • Intellectual disability designated by IQ\<70;
  • Has a DSM-5 or ICD-11 diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, brief psychotic disorder, psychotic disorder due to another medical condition, PTSD, antisocial personality disorder, or borderline personality disorder;
  • Has a primary diagnosis of ADHD (combined, inattentive, or hyperactivity/impulsive presentation);
  • Has a concurrent medical diagnosis that could significantly affect test performance such as brain injuries, Parkinson's disease, current epilepsy or active seizures, amyotrophic lateral sclerosis (ALS), multiple sclerosis, dementias (e.g. vascular dementia, Alzheimer disease, etc);
  • Has other conditions that could affect test performance (migraine or other types of severe headache, chronic or acute pain);
  • Use of prescription medications (e.g., anxiolytics, sedative medications) taken on the day before completing QbMobile that could significantly affect performance;
  • Substance use (e.g., alcohol, drugs) that may affect performance on the day of the tests.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CCM Clinical Research Group

Miami, Florida, 33133, United States

RECRUITING

MeSH Terms

Conditions

Bipolar DisorderAutism Spectrum DisorderAnxiety, SeparationPhobia, SocialGeneralized Anxiety Disorder

Condition Hierarchy (Ancestors)

Bipolar and Related DisordersMood DisordersMental DisordersChild Development Disorders, PervasiveNeurodevelopmental DisordersAnxiety DisordersPhobic Disorders

Central Study Contacts

Ragini Sanyal

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 11, 2025

First Posted

January 9, 2026

Study Start

January 1, 2026

Primary Completion (Estimated)

November 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

May 6, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Due to the nature of the research, limited access to supporting data may be granted upon reasonable request under confidentiality agreements from the corresponding sponsor.

Locations