Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery

NCT07326774 | Recruiting

• 1 other identifier: 2025/397
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery. Lumbar spinal procedures are commonly associated with significant postoperative pain, which may impair early mobilization and increase opioid consumption. In routine clinical practice, QIPB is increasingly used as part of multimodal analgesia to improve pain control and reduce opioid-related adverse effects. Adult patients scheduled for elective lumbar spinal surgery under general anesthesia will be followed according to routine clinical care. Postoperative analgesia will be managed with intravenous patient-controlled analgesia (PCA) using tramadol, with or without the addition of ultrasound-guided QIPB, based on the preference of the attending anesthesiologist. No intervention or treatment assignment will be performed by the investigators. Postoperative pain scores at rest and during movement, opioid consumption, need for rescue analgesics, incidence of nausea and vomiting, and patient satisfaction will be recorded during the first 24 hours after surgery. The findings of this study are expected to provide further clinical evidence regarding the effectiveness of QIPB as part of multimodal analgesia in lumbar spinal surgery.

Conditions

Postoperative Pain; Lumbar Spine Surgery; Postoperative Analgesia

Keywords

Quadro-Iliac Plane Block; QIPB; Ultrasound-Guided Regional Anesthesia; Lumbar Spinal Surgery; Postoperative Analgesia; Patient-Controlled Analgesia

Outcome Measures

Primary Outcomes (1)

• Postoperative Pain Intensity

  Postoperative pain intensity assessed using the Numeric Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst imaginable pain.

  Within the first 24 hours after surgery

Secondary Outcomes (4)

• Total Opioid Consumption

  Within the first 24 hours after surgery

• Requirement for Rescue Analgesia

  Within the first 24 hours after surgery

• Postoperative Nausea and Vomiting

  Within the first 24 hours after surgery

• Patient Satisfaction With Pain Management

  24 hours after surgery

Study Arms (2)

PCA + QIPB Group

Patients who receive standard postoperative intravenous patient-controlled analgesia (PCA) with tramadol in combination with ultrasound-guided Quadro-Iliac Plane Block (QIPB) as part of routine clinical care following lumbar spinal surgery.

Other: QIPB

PCA + LAI Group

Patients who receive standard postoperative intravenous patient-controlled analgesia (PCA) with tramadol alone without the addition of any regional analgesic block following lumbar spinal surgery. In addition, the surgeon will perform local anesthetic infiltration (LAI) of the incision site as part of the routine analgesia protocol.

Other: LAI

Interventions

QIPB OTHER

Quadro-Iliac Plane Block using local anesthetic.

PCA + QIPB Group

LAI OTHER

The surgeon will perform local anesthetic infiltration (LAI) of the incision site.

PCA + LAI Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18-65 years with ASA physical status I-III and body mass index \<35 kg/m² scheduled for elective posterior lumbar segmental instrumentation surgery under general anesthesia. All participants provide written informed consent prior to enrollment.

You may qualify if:

• Patients aged between 18 and 65 years
• American Society of Anesthesiologists (ASA) physical status I-III
• Body mass index (BMI) \<35 kg/m²
• Scheduled for elective posterior lumbar spinal instrumentation surgery under general anesthesia

You may not qualify if:

• Refusal to participate in the study
• Emergency surgery
• Local infection or hematoma at the block application site
• Previous surgery at the block application site
• Presence of coagulopathy
• Known allergy or toxicity to local anesthetics
• History of hematological, renal, or hepatic disease, or advanced respiratory or cardiac failure
• Chronic analgesic use, chronic alcohol consumption, or substance abuse
• Inability to speak Turkish or presence of language/communication barriers

Sponsors & Collaborators

• Fatih Sultan Mehmet Training and Research Hospital: lead

Study Sites (1)

Fatih Sultan Mehmet Training and Research Hospital

Istanbul, Istanbul, 34752, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Oznur Demiroluk, Assoc. Prof.

  Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Elif Acar Deger, Dr.

CONTACT

+905069435510; drelifacardeger@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: December 26, 2025
• First Posted: January 8, 2026
• Study Start: January 5, 2026
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: February 23, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)