Rectus Abdominis Muscle Parameters and Postoperative Opioid Consumption in Geriatric Patients

NCT07545824 | Not Yet Recruiting

• 1 other identifier: rektus kas kalınlığı
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing abdominal surgery. Preoperative ultrasonographic measurements will be performed during routine clinical care, and postoperative pain scores and analgesic requirements will be recorded within the first 24 hours. The findings may help improve individualized analgesic strategies by identifying patient-specific predictors of postoperative opioid needs.

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

• Postoperative Total Opioid Consumption

  Total opioid consumption within the first 24 hours after surgery will be recorded and converted to morphine equivalents (mg). This measure will be used to evaluate the association between ultrasound-derived rectus abdominis muscle parameters and postoperative analgesic requirements.

  First 24 hours postoperatively

Interventions

Ultrasound-Guided Rectus Sheath Block OTHER

Ultrasound-guided rectus sheath block will be performed as part of routine clinical practice in geriatric patients undergoing abdominal surgery. No additional intervention will be introduced for study purposes. Ultrasound-derived rectus abdominis muscle thickness and thickening fraction will be measured preoperatively, and postoperative opioid consumption and pain scores will be recorded within the first 24 hours.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of geriatric patients (≥65 years) scheduled for elective midline abdominal surgery at S.B.U. Haseki Training and Research Hospital. All participants will receive bilateral ultrasound-guided rectus sheath block as part of routine clinical practice under general anesthesia. Eligible patients who meet the inclusion criteria and provide written informed consent will be prospectively enrolled.

You may qualify if:

• Age ≥65 years
• Scheduled for elective midline abdominal surgery
• ASA physical status I-III
• Planned to receive bilateral ultrasound-guided rectus sheath block as part of routine clinical practice
• Provided written informed consent

You may not qualify if:

• Known allergy or hypersensitivity to local anesthetics
• Infection or skin lesion at the injection site
• Systemic infection or sepsis
• Coagulopathy (INR \>1.5 or platelet count \<100,000/mm³)
• Use of therapeutic anticoagulation not safely managed perioperatively
• History of previous midline laparotomy
• History of abdominal mesh implantation or abdominal wall reconstruction
• Significant abdominal wall pathology (e.g., large hernia) affecting anatomy
• Neuromuscular disease (e.g., myasthenia gravis, ALS, muscular dystrophy)
• Inability to perform required maneuver for dynamic ultrasound measurement
• Moderate to severe cognitive impairment or poor cooperation
• Body mass index (BMI) \>40 kg/m²
• Cachexia or severe malnutrition
• Chronic opioid use (≥3 months)
• Chronic pain syndromes requiring regular analgesic use

Sponsors & Collaborators

• Istinye University: lead

Study Sites (1)

Istinye Üniversity

Istanbul, Merkez Mahallesi, 34250, Turkey (Türkiye)

Location

Related Publications (2)

• Jeffries SD, Harutyunyan R, Morse J, Hemmerling TM. Investigation into the clinical performance of rectus sheath block in reducing postoperative pain following surgical intervention: A systematic review and meta-analysis of randomised controlled trials. Indian J Anaesth. 2024 Feb;68(2):142-152. doi: 10.4103/ija.ija_1099_23. Epub 2024 Jan 29.

  PMID: 38435659 RESULT

• Choi ES, Cho SH, Kim JH. Relationship between rectus abdominis muscle thickness and metabolic syndrome in middle-aged men. PLoS One. 2017 Sep 15;12(9):e0185040. doi: 10.1371/journal.pone.0185040. eCollection 2017.

  PMID: 28915276 RESULT

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

İlke Dolgun

CONTACT

5555485632; ilkeser2004@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assoc.prof

Study Record Dates

• First Submitted: April 16, 2026
• First Posted: April 22, 2026
• Study Start: April 25, 2026
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: April 22, 2026

Record last verified: 2026-04

Locations

TU (1)