M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery

NCT07311902 | Recruiting

• 1 other identifier: B.30.2.YYU.0.01.00.00/93
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room. Patients in both groups who are taken to the block room will be administered 1-2 mg iv midazolam for sedation. M TAPA block will be applied for the surgical procedure. After aseptic conditions are provided, the high-frequency linear US probe will be covered with a sterile sheath. The US probe will be placed in the saggital plane at the costochondral angle where the midclavicular line intersects the costal cartilage. 5 ml of saline will be injected using the in-plane technique using a 22G 100 mm block needle and the block location will be verified. After the block location is verified, a total of 20 ml of 0.25% bupivacaine will be injected unilaterally and the procedure will be terminated. After aseptic conditions are provided, the high-frequency linear US probe will be covered with a sterile sheath. In TAP block, the block needle will be advanced to the fascial plane between the internal oblique and transversus abdominis muscles with the in-plane technique and the procedure will be completed by injecting 5 ml 20 ml 0.25% bupivacaine unilaterally. The same analgesia protocol will be applied to both groups intraoperatively and postoperatively, and a survey will be conducted on the patients at the 24th hour postoperatively.

Conditions

Pain Management; Mtapa Block; TAP Block

Outcome Measures

Primary Outcomes (1)

• pain score

  Patients' pain scores will be evaluated

  The primary aim of our study was to compare VAS scores at 1, 2, 4, 8, 12, and 24 hours postoperatively and to evaluate the level of comfort.

Secondary Outcomes (1)

• The QoR-15 Patient Questionnaire, a 40-question global recovery rating system with a Turkish variant

  24 hours following surgery.

Study Arms (2)

Group T

ACTIVE COMPARATOR

The block needle will be advanced to the fascial plane between the internal oblique and transversus abdominis muscles by placing the USG transversely on the mid-axillary line between the iliac crest and subcostal planes. 5 ml saline will be injected and the block location will be confirmed. After the block location is confirmed, a total of 20 ml of 0.25% bupivacaine will be injected unilaterally and the procedure will be completed.

Procedure: TAP Block Group

Group M

ACTIVE COMPARATOR

Using the in-plane technique, the probe will be pushed slightly to visualize the lower part of the costochondral angle at the central level, the block needle will be advanced in the caudal-cranio direction, 5 ml of saline will be injected into the layer between the transverse abdominal muscle and the lower plane of the costal cartilage via a 22G 100 mm block needle and the block location will be confirmed. After the block location is confirmed, a total of 20 ml of 0.25% bupivacaine will be injected unilaterally and the procedure will be completed.

Procedure: M TAPA block

Interventions

TAP Block Group PROCEDURE

20 ml of 0.25% bupivacaine

Group T

M TAPA block PROCEDURE

20 ml of 0.25% bupivacaine

Group M

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may not qualify if:

• History of bleeding diathesis
• Allergy or sensitivity to local anesthetics and opioids
• Infection in the area where the block will be applied
• Alcohol or drug addiction
• Patients with a BMI \> 30
• Suspected pregnancy
• Women in pregnancy or lactation
• Patients with allergies to study drugs
• Patient refusal
• Use of anticoagulant agents
• Planning for elective unilateral open inguinal hernia repair surgery
• ASA I-II status
• Being between 18 and 65 years of age

Sponsors & Collaborators

• Erzurum Regional Training & Research Hospital: lead

Study Sites (1)

Erzurum Regional Education and Research Hospital

Erzurum, 25000, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

omer doymus

CONTACT

+905070370397; omerdoymus@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: June 18, 2025
• First Posted: December 31, 2025
• Study Start: November 1, 2024
• Primary Completion: April 1, 2025
• Study Completion: January 1, 2026
• Last Updated: December 31, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)