Transversus Abdominis Plane Block (TAP) Versus Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Laparoscopic Gynecologic Surgeries
1 other identifier
interventional
90
1 country
1
Brief Summary
Although laparoscopic techniques are considered minimally invasive surgical procedures with lower perioperative pain scores compared to open surgeries, they are still associated with significant levels of pain. This study aims to investigate the analgesic effectiveness of two routinely performed regional analgesic techniques in our clinic-ultrasound-guided classic bilateral TAP block and ultrasound-guided bilateral M-TAPA block-in patients undergoing laparoscopic gyneco-oncologic surgery (LGOS), as well as their effects on intraoperative opioid consumption.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 28, 2025
CompletedFirst Posted
Study publicly available on registry
May 29, 2025
CompletedStudy Start
First participant enrolled
May 30, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2025
CompletedMay 29, 2025
May 1, 2025
16 days
April 28, 2025
May 26, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Evaluation of intraoperative opioid consumption
during surgery
Secondary Outcomes (1)
Comparison of postoperative Visual Analog Scale (VAS) pain scores
postoperative first day
Study Arms (3)
control
NO INTERVENTIONgroup TAP
ACTIVE COMPARATORgroup M-TAPA
ACTIVE COMPARATORInterventions
Patients in the TAP group will receive a bilateral Transversus Abdominis Plane (TAP) block under ultrasound guidance prior to surgery after general anaesthesia, with the local anesthetic administered between the internal oblique and transversus abdominis muscles. A total of 40 mL of 0.25% bupivacaine will be used for the procedure.
Patients in the M-TAPA group will receive a bilateral Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) under ultrasound guidance prior to surgery after general anaesthesia. A total of 40 mL of 0.25% bupivacaine will be used for the procedure.
Eligibility Criteria
You may not qualify if:
- Neuropathy
- Chronic analgesic therapy
- Severe cardiopulmonary disease
- Uncontrolled diabetes mellitus (HbA1c \> 8%)
- Severe renal or hepatic failure
- Pregnancy or lactation
- Body mass index (BMI) greater than 35 kg/m²
- Local infection at the injection site
- Inability to comprehend pain scores or cooperate (e.g., Alzheimer's disease, mental retardation)
- Allergy to local anesthetic agents
- Refusal to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ankara Etlik City Hospital
Ankara, 06010, Turkey (Türkiye)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
April 28, 2025
First Posted
May 29, 2025
Study Start
May 30, 2025
Primary Completion
June 15, 2025
Study Completion
June 30, 2025
Last Updated
May 29, 2025
Record last verified: 2025-05
Data Sharing
- IPD Sharing
- Will not share