NCT07307391

Brief Summary

Background: Core body temperature increases in hot climates due to exercise workload, disrupting heat gain and loss of balance. The human thermoregulatory system regulates core body temperature through factors such as metabolic heat production, air temperature, humidity, and clothing. The study investigates physiological thermoregulatory responses in semiprofessional athletes during walking and jogging in different climatic conditions. Methods: A factorial experimental interventional design was used to evaluate different physical activity (low (L)=5 km/h and high (H)=8 km/h) and climatic conditions within the Thermal Environment Laboratory at Lund University, Sweden. The temperature within the climatic chamber was set at 40°C and 31°C, with a relative humidity of 20% and 70%, (hot dry (HD) and hot humid (HW), respectively, to account for a 28°C WBGT. The study used independent T-tests, ANOVA and simple linear regression models to analyse the physiological responses of semiprofessional athletes under different test conditions, comparing gender differences.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 7, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 10, 2025

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 12, 2025

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

December 14, 2025

Completed
15 days until next milestone

First Posted

Study publicly available on registry

December 29, 2025

Completed
Last Updated

December 31, 2025

Status Verified

December 1, 2025

Enrollment Period

5 months

First QC Date

December 14, 2025

Last Update Submit

December 26, 2025

Conditions

Keywords

Heat StressExposure timeGender differenceWBGT

Outcome Measures

Primary Outcomes (3)

  • Exposure Time

    duration an athlete is exposed to a specific intensity or environmental condition

    Just one day, the day of the test, in those weather conditions

  • Heart Rate

    measures how hard your heart works to gauge fitness

    Just one day, the day of the test, in those weather conditions

  • Oxygen Uptake

    how much oxygen your body uses during activity

    Just one day, the day of the test, in those weather conditions

Secondary Outcomes (6)

  • Core Body Temperature

    Just one day, the day of the test, in those weather conditions

  • Skin Temperature

    Just one day, the day of the test, in those weather conditions

  • Body Temperature

    Just one day, the day of the test, in those weather conditions

  • Sweat Rate

    Just one day, the day of the test, in those weather conditions

  • Perceived Exertion Level

    Just one day, the day of the test, in those weather conditions

  • +1 more secondary outcomes

Study Arms (4)

hot wet high (HWH)

EXPERIMENTAL

Air Temperature (ºC) 30.6±1.2 Relative Humidity (%) 68.6±1.3 Vapour Pressure (kPa) 1011±1.1 Bruel and Kjear (WBGT ºC) 27.3±0.8 Heat Stress (WBGT ºC) 27.8±0.8 Air Velocity (m/s) 0.45±0.19

Other: hot wet high (HWH)

hot dry high (HDH)

EXPERIMENTAL

Relative Humidity (%) 39.7±0.3 Vapor Pressure (kPa) 29.0±1.2 Bruel and Kjear (WBGT ºC) 1007.9± 6.4 Heat Stress (WBGT ºC) 28.9±0.6 Air Velocity (m/s) 28.4±0.3

Other: hot dry high (HDH)

hot dry low (HWL)

EXPERIMENTAL

Relative Humidity (%) 31.1±0.1 Vapor Pressure (kPa )67.1±1.0 Bruel and Kjear (WBGT ºC)1005.7±8.0 Heat Stress (WBGT ºC) 27.4±0.6 Air Velocity (m/s) 27.9±0.3

Other: Experimental: hot dry low (HWL)

hot wet low (HWL)

EXPERIMENTAL

Relative Humidity (%) 39.8±0.1 Vapor Pressure (kPa) 26.4±0.4 Bruel and Kjear (WBGT ºC) 1004.7±10.7 Heat Stress (WBGT ºC) 28.3±0.3 Air Velocity (m/s) 27.7±0.1

Other: Experimental: hot wet low (HWL)

Interventions

Relative Humidity (%) 39.8±0.1 Vapor Pressure (kPa) 26.4±0.4 Bruel and Kjear (WBGT ºC) 1004.7±10.7 Heat Stress (WBGT ºC) 28.3±0.3 Air Velocity (m/s) 27.7±0.1

hot wet low (HWL)

Air Temperature (ºC) 30.6±1.2 Relative Humidity (%) 68.6±1.3 Vapour Pressure (kPa) 1011±1.1 Bruel and Kjear (WBGT ºC) 27.3±0.8 Heat Stress (WBGT ºC) 27.8±0.8 Air Velocity (m/s) 0.45±0.19

hot wet high (HWH)

Relative Humidity (%) 39.7±0.3 Vapor Pressure (kPa) 29.0±1.2 Bruel and Kjear (WBGT ºC) 1007.9± 6.4 Heat Stress (WBGT ºC) 28.9±0.6 Air Velocity (m/s) 28.4±0.3

hot dry high (HDH)

Relative Humidity (%) 31.1±0.1 Vapor Pressure (kPa )67.1±1.0 Bruel and Kjear (WBGT ºC)1005.7±8.0 Heat Stress (WBGT ºC) 27.4±0.6 Air Velocity (m/s) 27.9±0.3

hot dry low (HWL)

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Participation at the regional competition level
  • Receiving monetary remuneration for their sports engagement
  • Participating in sports activities in the previous six years
  • Average training experience of 6.0±1.4 years
  • A weekly volume of 6.3±0.7 days for 2.3±0.7 hours (h)·day-¹.

You may not qualify if:

  • A 2 kg weight change in the previous month
  • Adherence to special diets
  • Use of nutritional supplements
  • Smoking
  • An acute or chronic communicable or noncommunicable disease
  • Heat allergic problems.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Health Sciences, University of Valladolid Soria Campus, Soria, Soria 42004

Soria, Soria, 42004, Spain

Location

MeSH Terms

Conditions

Heat Stress Disorders

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: A factorial experimental interventional study design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Doctor

Study Record Dates

First Submitted

December 14, 2025

First Posted

December 29, 2025

Study Start

July 7, 2025

Primary Completion

December 10, 2025

Study Completion

December 12, 2025

Last Updated

December 31, 2025

Record last verified: 2025-12

Locations