Cooling Solutions for Outdoor Workers

NCT06998667 | Completed

• 1 other identifier: 80246
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aim to test the effectiveness of two cooling interventions in reducing the core temperature of outdoor workers.

Conditions

Heat Acclimation and Thermotolerance; Hyperthermia

Keywords

outdoor work; heat stress; kidney injury; cooling interventions

Outcome Measures

Primary Outcomes (1)

• Core Temperature

  Rate of core temperature change as measured by core temperature pill

  up to 10 hours

Study Arms (3)

Standard Heat Illness Prevention

ACTIVE COMPARATOR

Standard CAL-OSHA workplace heat illness prevention interventions, which require availability of cool, potable water; availability of shade when temperatures exceed 80F; and encouragement of rest for cool down breaks.

Behavioral: Standard Heat Illness Prevention Measures

Cooling bandana with Standard Heat Illness Prevention Measures

EXPERIMENTAL

Provision of a bandana with slow-evaporation polymer for use during work, in addition to standard CAL-OSHA workplace heat illness prevention interventions

Behavioral: Standard Heat Illness Prevention Measures; Other: Cooling bandana

Cooling glove with standard Heat Illness Prevention

EXPERIMENTAL

Provision of a glove with ability to circulate cool water, for use during breaks, in addition to standard CAL-OSHA workplace heat illness prevention interventions

Behavioral: Standard Heat Illness Prevention Measures; Other: Cooling glove

Interventions

Standard Heat Illness Prevention Measures BEHAVIORAL

Standard CAL-OSHA workplace heat illness prevention interventions, which require availability of cool, potable water; availability of shade when temperatures exceed 80F; and encouragement of rest for cool down breaks

Cooling bandana with Standard Heat Illness Prevention Measures; Cooling glove with standard Heat Illness Prevention; Standard Heat Illness Prevention

Cooling glove OTHER

Cooling glove with ability to circulate cool water interface with palmar skin

Cooling glove with standard Heat Illness Prevention

Cooling bandana OTHER

Cooling bandana embedded with a polymer to slow evaporation

Cooling bandana with Standard Heat Illness Prevention Measures

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18
• Anticipated to be working in the same job category for the duration of the study
• Able to communicate in English or Spanish

You may not qualify if:

• Cannot provide informed consent
• Weight less than 40 kg
• Inability to swallow pills
• Known history of having a pacemaker or ICD
• Pregnancy as determined by self report and confirmed on Day 1
• Gastrointestinal disorders (e.g., gastroparesis, prior surgery on GI tract with the exception of appendectomy or cholecystectomy, diverticulosis or inflammatory bowel disease)
• Plan for an elective MRI in the 7 days post last planned pill ingestion

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

Location

MeSH Terms

Conditions

Hyperthermia; Heat Stress Disorders

Condition Hierarchy (Ancestors)

Body Temperature Changes; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Wounds and Injuries

Study Officials

• Shuchi Anand, MD

  Stanford University

  PRINCIPAL INVESTIGATOR

• Julie Parsonnet, MD

  Stanford University

  PRINCIPAL INVESTIGATOR

• Maria Montez Rath, mrath@stanford.edu

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor Emeritus in Medicine

Study Record Dates

• First Submitted: May 20, 2025
• First Posted: May 31, 2025
• Study Start: June 24, 2025
• Primary Completion: July 25, 2025
• Study Completion: January 5, 2026
• Last Updated: April 29, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)