Comparison of the Postoperative Analgesic Efficacy of SAP and SPSIP Blocks in Patients Undergoing Mammoplasty

NCT07302399 | Not Yet Recruiting

• 1 other identifier: AIBU-TF-AR-II-005
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to compare the postoperative analgesic efficacy of serratus anterior plane block (SAPB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing mammoplasty surgery. To this end, a double-blind, randomized, controlled study has been designed. Female patients aged 18-65 years who will undergo mammoplasty surgery will be included in the study. Postoperative pain levels, opioid consumption, duration of analgesic requirement, and patient satisfaction will be evaluated in patients who receive fascial blocks for analgesic purposes.

Conditions

Postsurgical Pain; Breast Pain; Postoperative Pain

Keywords

Mammoplasty; Postoperative Pain; SPSIP Block; SAP Block

Outcome Measures

Primary Outcomes (2)

• Total opioid consumption

  Tramadol will be prepared at a concentration of 10 mg/mL, and patient-controlled analgesia (PCA) will be administered without a basal infusion, using a lock-out interval of 20 minutes and a bolus dose of 20 mg.

  0, 1, 6, 12 and 24 hours

• Postoperative pain scores (Numerical rating scale: NRS),Between 0 and 10 points (11 points in total), as the score increases, the pain intensity increases.

  Postoperative 24 hours period. Patients' pain scores will be questioned at 0, 1, 6, 12 and 24 hours.

  0, 1, 6, 12 and 24 hours

Secondary Outcomes (2)

• Time to first analgesic requirement

  24 Hour

• Patient satisfaction score

  24 Hour

Study Arms (2)

SAPB Group

ACTIVE COMPARATOR

Serratus Anterior Plane Group Drug: 0,25% Bupivacaine 0,5ml/kg (max.20ml) will be used for blocks for each side.

Procedure: Serratus Anterior Plane Block

SPSIPB Group

EXPERIMENTAL

Serratus Posterior Superior Intercostal Plane Block Group Drug: 0,25% Bupivacaine 0,5ml/kg (max.20ml) will be used for blocks for each side.

Procedure: Serratus Posterior Superior Intercostal Plane Block

Interventions

Serratus Anterior Plane Block PROCEDURE

Application of ultrasound-guided serratus anterior plane block for perioperative analgesia for mammoplasty operations. Serratus anterior plane block will be administered under general anesthesia before the surgery Drug: Bupivacaine (Block Drug) For block performances, 0,25% Bupivacaine will be used at 0,5 ml/kg (max. 20cc) for each side.

Also known as: SAP Block

SAPB Group

Serratus Posterior Superior Intercostal Plane Block PROCEDURE

Application of ultrasound-guided serratus anterior plane block for perioperative analgesia for mammoplasty operations. Serratus posterior superior intercostal plane block will be administered under general anesthesia before the surgery Drug: Bupivacaine (Block Drug) For block performances, 0,25% Bupivacaine will be used at 0,5 ml/kg (max. 20cc) for each side.

Also known as: SPSIP Block

SPSIPB Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Gender Eligibility Details: Only females who are planned mammoplasty operation
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 18-85 years
• Patients undergoing elective mammoplasty
• ASA physical status I-II

You may not qualify if:

• Patients who refuse to participate
• Mentally disabled patients
• Presence of infection at the injection site
• Patients with coagulopathy
• History of allergy or toxicity to local anesthetics
• Patients with uncontrolled hypertension
• Patients with uncontrolled diabetes mellitus
• Patients with hepatic or renal failure
• Pregnant, breastfeeding women

Sponsors & Collaborators

• Çam Sakura Şehir Hastanesi: collaborator
• Istanbul Medipol University Hospital: collaborator
• Abant Izzet Baysal University: lead
• Karabuk Training and Research Hospital: collaborator

Study Sites (1)

Bolu Abant İzzet Baysal Medical School

Bolu, 14030, Turkey (Türkiye)

Location

Related Publications (1)

• Koksal BG, Baytar C, Bayraktar E, Balbaloglu H. Effects of serratus posterior superior intercostal plane block on postoperative analgesia in patients undergoing breast cancer surgery: a randomized controlled trial. BMC Anesthesiol. 2025 Apr 24;25(1):209. doi: 10.1186/s12871-025-03092-0.

  PMID: 40275145 BACKGROUND

MeSH Terms

Conditions

Pain, Postoperative; Mastodynia

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Kasım İlker İtal

CONTACT

+90 5337723300; ilkerital@gmail.com

Kenan Kart

CONTACT

+90 5386606553; kenankart@karabuk.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Double
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass. Prof. Dr

Study Record Dates

• First Submitted: December 11, 2025
• First Posted: December 24, 2025
• Study Start: February 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: January 13, 2026

Record last verified: 2026-01

Locations

TU (1)