Postoperative Analgesic Comparison of SPSI Block and SAP Block in Video-Assisted Thoracoscopic Surgery (VATS)

NCT06778642 | Not Yet Recruiting

• 1 other identifier: UU-AN-RBC-01
• Study Type: interventional
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

In our study, we primarily aimed to compare the postoperative analgesic effectiveness of the Serratus Posterior Superior Intercostal Plane Block and the Serratus Anterior Plane Block, both routinely applied in patients undergoing Video-Assisted Thoracoscopic Surgery (VATS)

Conditions

Acute Post Operative Pain

Outcome Measures

Primary Outcomes (1)

• The Numerical Rating Scale (NRS)

  Numerical Rating Scale (NRS) The Numerical Rating Scale (NRS) is a commonly used pain assessment tool that allows patients to rate their pain intensity on a scale from 0 to 10. 0 indicates no pain. 10 indicates the worst possible pain. Patients are asked to choose a number that best represents their pain level at the time of assessment.

  2 days

Study Arms (2)

Serratus Posterior Superior Intercostal Plane Block Group

ACTIVE COMPARATOR

In this group, the ultrasound device with a linear probe (38 mm, 6 MHz) will be used. The upper medial border of the scapula on the side of the planned surgery will be identified between the 2nd and 7th ribs. A block needle will be inserted medially to the scapula, advancing into the plane between the serratus posterior superior muscle and the intercostal muscles. A total of 30 ml of 0.25% bupivacaine will be injected, with a maximum dose of 2 mg/kg/day. In other words, the injection will be applied under the SPS muscle, between the rib and the SPS muscle.

Procedure: Serratus Posterior Superior Intercostal Plane Block

Serratus Anterior Plane Block Group

ACTIVE COMPARATOR

In this group, the ultrasound device with a linear probe (38 mm, 6 MHz) will be used. The probe will be placed between the anterior and posterior axillary lines, on the side of the planned surgery, between the 2nd and 7th ribs. The block needle will be advanced to the surface or deeper part of the serratus anterior muscle, into the fascial plane. A total of 30 ml of 0.25% bupivacaine will be injected, with a maximum dose of 2 mg/kg/day, underneath the serratus anterior muscle.

Procedure: Serratus Anterior Plane Block

Interventions

Serratus Posterior Superior Intercostal Plane Block PROCEDURE

Patients undergoing Video-Assisted Thoracoscopic Surgery (VATS) will receive either a Serratus Posterior Superior Intercostal Plane Block (SPSIPB) with bupivacaine after induction and before the surgical procedure begins.

Serratus Posterior Superior Intercostal Plane Block Group

Serratus Anterior Plane Block PROCEDURE

Patients undergoing Video-Assisted Thoracoscopic Surgery (VATS) will receive either a Serratus Anterior Plane Block (SAPB) with bupivacaine after induction and before the surgical procedure begins.

Serratus Anterior Plane Block Group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 18 to 80 years undergoing Video-Assisted Thoracoscopic Surgery (VATS)
• Scheduled at Uludağ University Faculty of Medicine Hospital Operating Room
• Classified as ASA I, II, or III according to the American Society of Anesthesiologists (ASA) criteria

You may not qualify if:

• Allergy to local anesthetics or contraindications to bupivacaine
• Known or suspected coagulopathy
• Infection at the injection site
• History of thoracic surgery
• Severe neurological or psychiatric disorders
• Severe cardiovascular disease
• Liver failure
• Renal failure (glomerular filtration rate \< 15 ml/min/1.73 m²)
• Chronic opioid use

Sponsors & Collaborators

• Uludag University: lead

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: The researchers and participants will be double-blinded
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident Doctor

Model Details: The study will include patients aged 18-80 years scheduled for VATS at Uludağ University Medical Faculty Hospital. Patients with ASA I, II, and III classifications will be included. Patients will be randomized into two groups: Group 1: SPSIPB Group 2: SAPB

Study Record Dates

• First Submitted: January 12, 2025
• First Posted: January 16, 2025
• Study Start: May 15, 2025
• Primary Completion: February 9, 2026
• Study Completion: February 10, 2026
• Last Updated: May 15, 2025

Record last verified: 2025-05